Daily Archives: March 30, 2017

Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease

30 Mar, 2017 | 17:34h | UTC

Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Challenges and Potential Solutions – Annals of Internal Medicine (free)

 

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A National Strategy for the Elimination of Hepatitis B and C

30 Mar, 2017 | 17:23h | UTC

A National Strategy for the Elimination of Hepatitis B and C: Phase Two Report – National Academies of Sciences, Engineering, and Medicine(free)

Press release: U.S. Could Be Rid of Hepatitis B and C as Public Health Problems, Preventing Nearly 90,000 Deaths by 2030, With Better Attention to Prevention, Screening, Treatment, and Creative Financing for Medicines (free)

See also: Phase One Report (free)

U.S. Strategy for the Elimination of Hepatitis B and C.

 

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Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease

30 Mar, 2017 | 17:27h | UTC

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease – Journal of the American College of Cardiology (free)

Source: SciCombinator

Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.

 

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Erectile dysfunction in men exposed to the 5α-reductase inhibitors

30 Mar, 2017 | 17:25h | UTC

Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride – PeerJ (free)

Source: SciCombinator

Observational data suggests there might be a link.

 

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Exposing peer review

30 Mar, 2017 | 17:22h | UTC

Exposing peer review – Research Information (free) (RT @Sab_Ra)

See also other recent commentaries on the peer review system

 

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100 Objects That Shaped Public Health

30 Mar, 2017 | 17:32h | UTC

100 Objects That Shaped Public Health: From the Obscure to the Everyday, These Objects Tell the Story – Global Health NOW (free)

Very interesting compilation with 100 objects that have made their mark on public health (for better or worse).

 

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Thu, Mar 30 – Top 10 Medical News Stories

30 Mar, 2017 | 00:01h | UTC

 

1 – 100 Objects That Shaped Public Health: From the Obscure to the Everyday, These Objects Tell the Story – Global Health NOW (free)

Very interesting compilation with 100 objects that have made their mark on public health (for better or worse).

 

2 – Press release: WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years – World Health Organization (free)

See also: WHO’s work on patient safety (free) AND WHO Global Patient Safety Challenge on Medication Safety (free) AND WHO Educational materials for medication safety (free)

 

3 – Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease – Journal of the American College of Cardiology (free)

Source: SciCombinator

Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.

 

4 – Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Challenges and Potential Solutions – Annals of Internal Medicine (free)

 

5 – Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride – PeerJ (free)

Source: SciCombinator

Observational data suggests there might be a link.

 

6 – Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)

See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)

This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.

 

7 – A National Strategy for the Elimination of Hepatitis B and C: Phase Two Report – National Academies of Sciences, Engineering, and Medicine (free)

Press release: U.S. Could Be Rid of Hepatitis B and C as Public Health Problems, Preventing Nearly 90,000 Deaths by 2030, With Better Attention to Prevention, Screening, Treatment, and Creative Financing for Medicines (free)

See also: Phase One Report (free)

U.S. Strategy for the Elimination of Hepatitis B and C.

 

8 – Five ways consortia can catalyse open science – Nature (free)

 

9 – Exposing peer review – Research Information (free) (RT @Sab_Ra)

See also other recent commentaries on the peer review system

 

10 – Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation – Centre for Evidence-Based Medicine, University of Oxford (free)

 

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Prevention of everolimus-related stomatitis

30 Mar, 2017 | 17:24h | UTC

Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)

See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)

This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.

 

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WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years

30 Mar, 2017 | 17:30h | UTC

Press release: WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years – World Health Organization (free)

See also: WHO’s work on patient safety (free) AND WHO Global Patient Safety Challenge on Medication Safety (free) AND WHO Educational materials for medication safety (free)

 

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Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation

30 Mar, 2017 | 17:20h | UTC

Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation – Centre for Evidence-Based Medicine, University of Oxford (free)

 

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