Thu, September 21 – 10 Stories of The Day!

1 – The world is running out of antibiotics, WHO report confirms – World Health Organization (free)

See WHO Reports: Antibacterial Agents in Clinical Development (free) AND Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics (free)

See also WHO Resources on Antibiotic Resistance

Commentaries: WHO report paints dire picture of antibiotic development – CIDRAP (free) AND Too few antibiotics in pipeline to tackle global drug-resistance crisis, WHO warns – The Guardian (free) AND The world is running out of antibiotics, WHO says – CNN (free text and video)

2 – Rapid Recommendation: Corticosteroids for sore throat: a clinical practice guideline – The BMJ (free text and infographic)

See also other Rapid Recommendations from The BMJ (all free)

3 – Improving health systems in low-income countries – 3 New Cochrane Library Reviews

Article 1: Implementation strategies for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Implementation strategies for health systems in low-income countries (free)

Article 2: Governance arrangements for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Effects of governance arrangements for health systems in low-income countries (free)

Article 3: Delivery arrangements for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Effects of delivery arrangements for health systems in low-income countries (free)

4 – Comprehensive geriatric assessment for older adults admitted to hospital – Cochrane Library (free)

Original article: Comprehensive geriatric assessment for older adults admitted to hospital – Cochrane Library (link to abstract – $ for full-text)

Related: Comprehensive assessment may reduce risk of delirium after hip fracture – NIHR Signal (free)

“Older patients are more likely to be alive and in their own homes at follow-up if they received comprehensive geriatric assessment on admission to hospital”.

5 – Low alcohol consumption and pregnancy and childhood outcomes: time to change guidelines indicating apparently ‘safe’ levels of alcohol during pregnancy? A systematic review and meta-analyses – BMJ Open (free)

Commentaries: No change to alcohol guidelines for pregnancy – NHS Choices (free) Health risks of light drinking in pregnancy confirms that abstention is the safest approach – The Conversation (free)

6 – Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010–11 and 2011–12 – Vaccine (link to abstract – $ for full-text)

Commentaries: Study signals association between flu vaccine, miscarriage – CIDRAP (free) AND New study finds link between flu vaccine and miscarriage. But is it real? – Science (free) AND Study shows miscarriage risk may have increased after flu shots, puzzling researchers – STAT (free) AND A new finding of a possible flu shot-miscarriage link shows science prioritizes vaccine safety – STAT (free)

“This study does not and cannot establish a causal relationship between repeated influenza vaccination and SAB, but further research is warranted”.

7 – Metabolically Healthy Obese and Incident Cardiovascular Disease Events Among 3.5 Million Men and Women – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: New evidence shows that healthy obesity is a myth – The Conversation (free) AND Study shows so-called ‘healthy obesity’ is harmful to cardiovascular health – Medical News Today (free) AND Obesity, even without other risk factors, leads to higher rate of cardiovascular disease – STAT (free) AND Another Study Challenges Notion of ‘Healthy Obese’ – TCTMD (free)

See related article and commentaries in our August 21^st issue (see #1)

8 – Expert consensus document: A ‘diamond’ approach to personalized treatment of angina – Nature Reviews Cardiology (free)

9 – What Does the Future Hold for Scientific Journals? Visual Abstracts and Other Tools for Communicating Research – Clinics in Colon and Rectal Surgery (free)

10 – Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis: The ACOSOG Z0011 (Alliance) Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Author interview: Breast Cancer Surgery: Less Is More (free audio)

Commentary: In Treating Breast Cancer, Less Can Be As Good As More – American Council on Science and Health (free)