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NEWS - TOP 10

Wed, August 15 – 10 Stories of The Day!

15 Aug,2018

 

1 – State of the Art Review: Overdiagnosis in primary care: framing the problem and finding solutions – The BMJ (free for two weeks)

 

2 – Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations – Nature Genetics (link to abstract – $ for full-text)

Commentaries: Researchers predict risk for common deadly diseases from millions of genetic variants – Broad Institute of MIT and Harvard, ScienceDaily (free) AND Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA – The New York Times (10 articles per month are free) AND Multi-gene test may find risk for heart disease and more – Associated Press (free) AND A Harvard Scientist Thinks He Has a Gene Test for Heart Attack Risk. He Wants to Give It Away Free – Forbes (free)

  

3 – Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video Summary: Fixed-Dose Combination Pill for Hypertension Treatment in Sri Lanka (free)

Commentaries: Three-in-one pill lowers blood pressure significantly, study say – UPI (free) AND Innovative triple pill significantly lowers blood pressure, study finds – George Institute for Global Health, via EurekAlert (free)

 

4 – Richard Smith: The polypill and the long journey to major impact – The BMJ Opinion (free)

Related Reviews: Strengths and Limitations of Using the Polypill in Cardiovascular Prevention – Current Cardiology Reports (free) AND The polypill approach – An innovative strategy to improve cardiovascular health in Europe – BMC Pharmacology and Toxicology (free)

 

5 – Cancer in People Living with HIV – NCCN Clinical Practice Guidelines in Oncology – Journal of the National Cancer Center Network (free)

 

6 – Opinion: Lessons for physicians from ‘The Bleeding Edge’: If you see something, say something – STAT (free)

“…physicians must act decisively when they identify the rare outlier in their midst. To do anything less would risk our credibility. Worse still, it could risk the lives of the people we took an oath not to harm.”

 

7 – Yoga, Depression, & Clinical Trial Critique 101 – Hilda Bastian, in Absolutely Maybe Blog (free)

“5 steps to unpack a randomized trial!” (via @hildabast, see Tweet)

 

8 – DRC Ebola cases surpass earlier outbreak total, virus infects 4 more health workers – CIDRAP (free)

Related: DRC may provide model for containing future Ebola outbreaks – The Conversation (free)

 

9 – Book: Diabetes in America, 3rd Edition – National Institutes of Health (free chapters)

News Release: New NIH reference book is one-stop resource for diabetes medical information – National Institutes of Health (free)

 

10 – Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews – Cochrane Library (free)

Summary: Treatments to improve pregnancy outcomes for women who develop diabetes during pregnancy: an overview of Cochrane systematic reviews – Cochrane Library (free)

 

Tue, August 14 – 10 Stories of The Day!

14 Aug,2018

 

1 – Clinically applicable deep learning for diagnosis and referral in retinal disease – Nature Medicine (free for a limited period)

Commentaries: Opening the ‘black box,’ Google DeepMind AI system diagnoses eye diseases and shows its work – STAT (free) AND Artificial intelligence tool ‘as good as experts’ at detecting eye problems – The Guardian (free)

 

2 – Automated deep-neural-network surveillance of cranial images for acute neurologic events – Nature Medicine (free for a limited period)

Commentaries: Artificial Intelligence Platform Screens for Acute Neurological Illnesses at Mount Sinai – Mount Sinai Health System, via NewsWise (free) AND AI diagnoses neurological diseases on CT in 1.2 seconds – Health Imaging (free) AND New AI system can screen for neurological illnesses in seconds – UPI (free)

 

3 – Screening for Urinary Incontinence in Women: A Recommendation From the Women’s Preventive Services Initiative – Annals of Internal Medicine (free)

Commentaries: WPSI says screen all women annually for urinary incontinence – American College of Physicians, via EurekAlert (free)

 

4 – Diagnosis of Invasive Fungal Diseases in Haematology and Oncology. 2018 Update of the Recommendations of the Infectious Diseases Working Party of the German Society for Hematology and Medical Oncology (AGIHO) – Mycosis (free PDF)

 

5 – American Academy of Family Physicians: Twenty Things Physicians and Patients Should Question (free)

Commentary: Choosing Wisely: New Practices to Avoid in Family Medicine – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UKChoosing Wisely Australia AND Choosing Wisely Canada

 

6 – Analysis of clinical benefit, harms, and cost-effectiveness of screening women for abdominal aortic aneurysm – The Lancet (free)

Commentaries: Should we screen women for abdominal aortic aneurysm? – The Lancet (free) AND Cost-Effectiveness of Screening Women for AAA – American College of Cardiology (free) AND Women Likely Not Good Targets for AAA Screening, Study Suggests – TCTMD (free)

 

7 – Prevalence and Estimated Economic Burden of Substandard and Falsified Medicines in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: Prevalence of Substandard and Falsified Essential Medicines: Still an Incomplete Picture – JAMA Network Open (free) AND New Study Finds Fake, Low-Quality Medicines Prevalent in the Developing World – University of North Carolina at Chapel Hill, via R&D (free)

 

8 – Evaluating Shared Decision Making for Lung Cancer Screening – JAMA Internal Medicine (free for a limited period)

Editorial: Failing Grade for Shared Decision Making for Lung Cancer Screening (free for a limited period)

Author Interview: Evaluating Shared Decision Making for Lung Cancer Screening (free audio)

Commentaries: Doctors may not explain pros, cons of lung cancer screening – Reuters (free) AND Shared Decision-Making Flops for Lung Ca Screening – MedPage Today (free registration required)

 

9 – Perspective: Surrogate End Points Ain’t all that Bad – The Health Care Blog (free) (via @RogueRad)

 

10 – Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: Early type 1 diabetes shortens women’s lives by 18 years – University of Gothenburg, via ScienceDaily (free) AND Early age type 1 diabetes linked to shorter life expectancy than later age diagnosis – OnMedica (free)

 

Mon, August 13 – 10 Stories of The Day!

13 Aug,2018

 

1 – Corticosteroid therapy for sepsis: a clinical practice guideline – The BMJ (free)

 

2 – Outbreaks: Behind the headlines – World Health Organization (free)

 

3 – Risk Factors Associated With Major Cardiovascular Events 1 Year After Acute Myocardial Infarction – JAMA Network Open (free)

Commentaries: Algorithm IDs Patients at Risk of Post-MI Events – MedPage Today (free registration required) AND Risk Model Helps Predict CV Events 1 Year After Acute MI – Medscape (free registration required)

 

4 – Analysis: Renaming low risk conditions labelled as cancer – The BMJ (free for a limited period)

Commentaries: Is it time to remove the cancer label from low-risk conditions? – The Conversation (free) AND Doctors should avoid saying ‘cancer’ for minor lesions – study – The Guardian (free) Drop ‘cancer’ label to protect patients from over-treatment, researchers say – The Sidney Morning Herald (free)

 

5 – Review: Dos and Don’ts in the Management of Cirrhosis: A View from the 21st Century – American Journal of Gastroenterology (via @Abraham_RMI)

 

6 – The multivitamin industry rakes in billions of dollars. But science says we’re not getting healthier – by Timothy Caulfield, in NBC News THINK (free)

Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)

“Unless you have a clinically identified deficiency, the research tells us there is little reason to consume supplements.”

 

7 – Tick- and Mosquito-Borne Diseases Are Increasing Dramatically – Scientific American (free)

Related: CDC Report: U.S Trends in Vector-borne Diseases (link to report and commentaries)

 

8 – Infographic: High burden, low budget: non-communicable diseases in low- and middle-income countries – Institute for Health Metrics and Evaluation (free) (via @equitylist)

 

9 – Multifactorial and multiple component interventions for preventing falls in older people living in the community – Cochrane Library (free)

Summary: Featured Review: Multifactorial and multiple component interventions for preventing falls in older people living in the community – Cochrane Library (free)

 

10 – Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016 – Kidney International (free)

News release and visual abstract: KI article shows the doubling incidence, prevalence and mortality of CKD – International Society of Nephrology (free)

Commentary: Global Burden of Kidney Disease on the Rise, Unequally Distributed – Medscape (free registration required)

 

Fri, August 10 – 10 Stories of The Day!

10 Aug,2018

 

1 – Dietary Diversity: Implications for Obesity Prevention in Adult Populations: A Science Advisory From the American Heart Association – Circulation (free PDF)

News Release: A diverse diet may not be the healthiest one (free)

Commentary: Diet Recommendations for Obesity Prevention: Time to Ditch Diversity (free)

Top Ten Things to Know: Dietary Diversity: Implications for Obesity Prevention in Adult Populations (free PDF)

 

2 – Opioid prescribing decreases after learning of a patient’s fatal overdose – Science (free for a limited period)

Commentary: Notification of patient overdose deaths reduces clinician opioid prescriptions – NIH News Releases (free) AND Clinicians were told their patient had died of an overdose. Then opioid prescribing dropped – STAT (free)

 

3 – Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis – The Lancet Psychiatry (free)

Commentaries: Refining treatment choices for ADHD – The Lancet Psychiatry (free) AND ADHD medications: Of all available drugs, methylphenidate should be first option for short-term treatment in children – ScienceDaily (free) AND Analysis of ADHD Drugs: Use Methylphenidate in Kids, Amphetamines in Adults – Physician’s First Watch (free)

Related: Cochrane Review: Adverse Events of Methylphenidate for ADHD in Children and Adolescents (link to abstract and free summary) AND Short Review: Stimulants for ADHD in children (free) AND Opinion: Drug treatment of ADHD – tenuous scientific basis (free)

 

4 – Viewpoint: Clinical Practice Guidelines: What’s Next? – JAMA (free for a limited period)

 

5 – Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study – The Lancet (link to abstract – $ for full-text)

Commentary: Lancet Paper Adds To Evidence That Reducing Salt To Very Low Levels May Be Dangerous – CardioBrief (free)

Related Report: Salt intake and Cardiovascular Disease (free report and commentaries)

 

6 – Are the “Best Buys” for Alcohol Control Still Valid? An Update on the Comparative Cost-Effectiveness of Alcohol Control Strategies at the Global Level – Journal of Studies on Alcohol and Drugs (free)

Commentary: Higher alcohol taxes are cost-effective in reducing alcohol harms – ScienceDaily (free)

Related: To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Policy lessons from health taxes (free research and commentaries)

 

7 – Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

 

8 – Scaled deployment of Wolbachia to protect the community from Aedes transmitted arboviruses – Gates Open Research (free)

Commentary: Dengue rates plummet in Australian city after release of modified mosquitoes – Nature News (free)

 

9 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

Related: DRC probes more suspected Ebola cases, rules out 3 – CIDRAP (free) AND War zone complicates roll-out of Ebola vaccine in latest outbreak – Nature News (free)

 

10 – Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: How common is endometrial cancer in women with postmenopausal bleeding? – eCancer News (free) AND Postmenopausal Bleeding: Reliable Sign of Endometrial Cancer – Medscape (free registration required)

 

Thu, August 9 – 10 Stories of The Day!

9 Aug,2018

 

1 – Practice guideline update recommendations summary: Disorders of consciousness – American Academy of Neurology (free PDF)

Related: Ethical, palliative, and policy considerations in disorders of consciousness – Neurology (free PDF) AND Comprehensive systematic review update summary: Disorders of consciousness – Neurology (free PDF)

Commentaries: New Guideline Released for Managing Vegetative and Minimally Conscious States – American Academy of Neurology, via NewsWise (free) AND Groups Issue New Disorders of Consciousness Guidelines – MedPage Today (free registration required)

 

2 – Labor Induction versus Expectant Management in Low-Risk Nulliparous Women – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Labor Induction versus Expectant Management in Low-Risk Women (free)

Commentaries: Induced labor at 39 weeks may reduce likelihood of C-section, NIH study suggests – NIH News Releases (free) AND Pregnancy Debate Revisited: To Induce Labor, Or Not? – NPR (free)

 

3 – Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth – New England Journal of Medicine (free)

Commentary: Maternal Vitamin D Supplementation Doesn’t Improve Infant Growth – Physician’s First Watch (free)

 

4 – Outcomes of Cardiac Screening in Adolescent Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Footballer heart death risk ‘underestimated’ – BBC (free) AND No Easy Answers on Best Heart Check-Up for Young Athletes – Associated Press, via NYT (free)

 

5 – Would technology enabled remote consulting save time and add value in primary care? – The BMJ Opinion (free)

“Would remote consulting save time and add value in primary care? Rising multimorbidity makes the evaluation of potentially time saving technologies ever more necessary” (via @bmj_latest see Tweet)

 

6 – Treatment for Bipolar Disorder in Adults: A Systematic Review – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

 

7 – WHO MERS Global Summary and Assessment of Risk – World Health Organization (free PDF)

Commentary: WHO highlights ongoing hospital MERS outbreak threat – CIDRAP (free)

 

8 – Perspective: Addressing Barriers to Inclusion of Pregnant Women in Clinical Trials – JAMA (free for a limited period)

 

9 – Publication bias: The answer to your research question may be sitting in somebody’s file drawer – Students 4 Best Evidence (free)

Related: Bias in medical research: A glossary of common research biases – First10Em (free) Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)

 

10 – Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentaries: Expert reaction to physical activity linked to improved mental health – Science Media Centre (free) AND Regular exercise ‘best for mental health’ – BBC (free) AND Exercise is good for your body and your mind, study says – CNN (free)

 

Wed, August 8 – 10 Stories of The Day!

8 Aug,2018

 

1 – Screening for Atrial Fibrillation With Electrocardiography: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Screening for Atrial Fibrillation Comes With Many Snags (free for a limited period) AND Electrocardiography Screening for Atrial Fibrillation: We Can Do Better (free for a limited period)

Author Interview: USPSTF Recommendation: Screening for Atrial Fibrillation With Electrocardiography (free audio)

“The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for atrial fibrillation with ECG. (I statement)”

 

2 – Mortality effects of timing alternatives for hip fracture surgery – Canadian Medical Association Journal (free)

Commentaries: Lower death rate when senior hip fractures are repaired quickly – Reuters (free) AND Delayed surgery for hip fractures cause of preventable deaths, study finds – The Globe and Mail (free) AND The sun should not set twice before hip fracture repair – CMAJ, via ScienceDaily (free)

 

3 – Update: Interim Guidance for Preconception Counseling and Prevention of Sexual Transmission of Zika Virus for Men with Possible Zika Virus Exposure — United States, August 2018 – CDC, MMWR (free)

Related: Vital Signs: Zika-Associated Birth Defects and Neurodevelopmental Abnormalities Possibly Associated with Congenital Zika Virus Infection — U.S. Territories and Freely Associated States, 2018 – CDC, MMWR (free)

Commentaries: 1 in 7 kids exposed to Zika in utero suffers defects, delays – CIDRAP (free) AND 1 in 7 babies exposed to Zika in the womb have health problems, CDC reports – STAT (free) AND One in 7 babies prenatally exposed to Zika has health problems, CDC says – CNN (free)

 

4 – Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis – Critical Care (free)

 

5 – The use of viscoelastic haemostatic assays in the management of major bleeding: A British Society for Haematology Guideline – British Journal of Haematology (free)

Source: Critical Care Reviews Newsletter

 

6 – Perspective: Workplace Wellness Programs Don’t Work Well. Why Some Studies Show Otherwise. – The New York Times (10 articles per month are free)

 

7 – Last Month in Oncology with Dr. Bishal Gyawali: July 2018 – eCancer News (free)

 

8 – Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

Commentaries: Prioritize cardiac monitoring for high-risk breast cancer patients, study suggests – ACP Internist (free) AND Cardiac monitoring may benefit high-risk breast cancer patients against heart failure – Cardiovascular Business (free) AND After Cardiotoxic Chemo, Less Than Half of Women With Breast Cancer Get Recommended Monitoring – TCTMD (free) AND Study Shows Importance of Cardiac Monitoring in High-Risk Breast Cancer Patients – American College of Cardiology (free)

 

9 – Special Issue: Roles of Physicians in Healthy Dying- AMA Journal of Ethics (free articles)

“What the roles of clinicians and patients should be in defining what constitutes a quality dying experience and good care of dying people has received less attention than issues like euthanasia and assisted death. Which parts of dying, if any, should be medicalized and why? What do patients and clinicians need to know about dying and why? The August 2018 issue of the AMA Journal of Ethics explores these and other questions.”

 

10 – Twelve-Month Outcomes After Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients: A Single-Group Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Patients who accepted infected kidneys cured of hepatitis C – STAT (free) AND Good Outcomes for HCV-Negative Recipients of HCV Kidneys – Renal & Urology News (free)

 

Tue, August 7 – 10 Stories of The Day!

7 Aug,2018

 

1 – Sedentary Behaviors in Today’s Youth: Approaches to the Prevention and Management of Childhood Obesity: A Scientific Statement From the American Heart Association – Circulation (free PDF)

News release: New tools, old rules: limit screen-based recreational media at home – AHA/ASA Newsroom (free)

 

2 – Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases – Hepatology (free)

 

3 – AGO Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2018 – German Gynecological Oncology Group (free)

 

4 – AGO Recommendations for the Diagnosis and Treatment of Patients with Advanced and Metastatic Breast Cancer: Update 2018 – German Gynecological Oncology Group (free)

 

5 – Patient–physician gender concordance and increased mortality among female heart attack patients – PNAS (link to abstract – $ for full-text)

Commentaries: Women More Likely to Survive Heart Attacks If Treated by Female Doctors – The Atlantic (free) AND Women survive a heart attack more often when their doctor is female, study finds – STAT (free) AND Women survive heart attacks better with women doctors – Washington University in St. Louis, via ScienceDaily (free)

 

6 – Review: Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free)

 

7 – Review: Liver enzymes: No trivial elevations, even if asymptomatic – Cleveland Clinic Journal of Medicine (free)

 

8 – Opinion: Anti-Vaccine Activists Have Taken Vaccine Science Hostage – The New York Times (10 articles per month are free)

“Should researchers not publish findings when there’s a chance they might be misinterpreted and scare the public?” (via @NYTHealth see Tweet)

 

9 – Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews – Cochrane Library (link to abstract – $ for full-text)

Summary: An overview of Cochrane Reviews on red blood cell transfusions to treat or prevent sickle cell disease-related complications – Cochrane Library (free)

 

10 – Microvascular Outcomes in Patients With Diabetes After Bariatric Surgery Versus Usual Care: A Matched Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Bariatric Surgery for Diabetes May Halve the Risk for Microvascular Disease – NEJM Physician’s First Watch (free) AND Bariatric surgery linked to significant reduction in microvascular complications of type 2 diabetes – MedicalXpress (free)

 

Mon, August 6 – 10 Stories of The Day!

6 Aug,2018

 

1 – Delirium in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)

 

2 – Comparison of Clinical Outcomes Among Patients With Atrial Fibrillation or Atrial Flutter Stratified by CHA2DS2-VASc Score – JAMA Network Open (free)

Commentaries: Ischemic Stroke Risk Scoring May Not Be Accurate for Patients with Atrial Flutter – TCTMD (free) AND Don’t Group Afib, Atrial Flutter Together in Evaluating Stroke Risk – MedPage Today (free registration required)

 

3 – The Surviving Sepsis Campaign: A Rush to Judgment – NEJM Journal Watch (free)

Original Guideline: The Surviving Sepsis Campaign Bundle: 2018 update – Intensive Care Medicine (free)

Related Opinion: Petition to retire the surviving sepsis campaign guidelines – PulmCrit (free)

 

4 – Playing Doctor with Watson: Medical Applications Expose Current Limits of AI – Spiegel (free) (via @EricTopol)

“IBM has big plans for how its Watson artificial intelligence software could change the medical industry. But a number of hospitals have ended their experiments with the platform, arguing that it doesn’t help diagnose or treat diseases.”

 

5 – Bias in medical research: A glossary of common research biases – First10Em (free) (via @pash22)

Related: Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)

 

6 – The Illness Is Bad Enough. The Hospital May Be Even Worse – The New York Times (10 articles per month are free)

Related: Post-Hospital Syndrome — An Acquired, Transient Condition of Generalized Risk – New England Journal of Medicine (free) AND Is Posthospital Syndrome a Result of Hospitalization-Induced Allostatic Overload? – Journal of Hospital Medicine (free) (via @hmkyale)

“The elderly are particularly vulnerable to “post-hospital syndrome,” some experts believe, and that may be why so many patients return.”

 

7 – Quantifying excess deaths related to heatwaves under climate change scenarios: A multicountry time series modelling study – PLOS Medicine (free)

Commentaries: Heatwave deaths will rise steadily by 2080 as globe warms up – Monash University, via ScienceDaily (free) AND Heatwave deaths likely to rise steadily by 2080 without appropriate climate and health policies – London School of Hygiene & Tropical Medicine (free)

Related Lancet Editorial: Heatwaves and health (free)

Related Report: Lancet Countdown: Traking Progress on Health and Climate Change (free report, commentaries, infographics, video and other resources)

 

8 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

Related: Conflict in new Ebola zone of DR Congo exacerbates complexity of response: WHO emergency response chief – UN News (free) AND WHO: Ebola DRC outbreak taking place in ‘war zone’ – CIDRAP (free) AND Ebola In A Conflict Zone – NPR (free) AND WHO sees complex vaccine and security questions in Ebola response – Reuters (free)

 

9 – Colloids versus crystalloids for fluid resuscitation in critically ill people – Cochrane Library (link to abstract – $ for full-text)

Summary: Colloids or crystalloids for fluid replacement in critically people – Cochrane Library (free)

Using starches, dextrans, albumin or FFP (moderate-certainty evidence), or gelatins (low-certainty evidence), versus crystalloids probably makes little or no difference to mortality. Starches probably slightly increase the need for blood transfusion and RRT (moderate-certainty evidence), and albumin or FFP may make little or no difference to the need for renal replacement therapy (low-certainty evidence)”.

 

10 – Peer-supported self-management for people discharged from a mental health crisis team: a randomised controlled trial – The Lancet (free)

Commentaries: Peer-delivered self-management programmes in mental health – The Lancet (free) AND After the crisis: self-management and peer-support – The Mental Elf (free) AND Peer Support Helps Reduce Mental Crisis Readmissions – MedPage Today (free registration required)

 

Fri, August 3 – 10 Stories of The Day!

3 Aug,2018

 

1 – National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of heart failure 2018 – The Medical Journal of Australia (free for 10 days)

 

2 – National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the diagnosis and management of atrial fibrillation 2018 – The Medical Journal of Australia (free for 10 days)

 

3 – Diagnosis, treatment and prevention of pediatric obesity: consensus position statement of the Italian Society for Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics – Italian Journal of Pediatrics (free)

 

4 – The Top 10 Pulmonary Pearls for Primary Care Physicians – Mayo Clinic Proceedings (free for a limited period)

 

5 – Cardiovascular and Other Health Benefits of Sauna Bathing: A Review of the Evidence – Mayo Clinic Proceedings (free for a limited period)

Commentaries: Regular sauna users may have fewer chronic diseases – Reuters (free) AND Saunas Linked to Numerous Health Benefits – Medscape (free registration required) AND Frequent sauna bathing has many health benefits – Elsevier, via ScienceDaily (free)

 

6 – No proof that moderate drinking prevents dementia – NHS Choices (free)

See original study: Alcohol consumption and risk of dementia (free text, editorial and commentaries)

“”Middle aged drinking may reduce dementia risk, new study finds,” is the misleading and irresponsible headline in The Daily Telegraph.”

 

7 – Viewpoint: Lyme Disease in 2018: What Is New (and What Is Not) – JAMA (free for a limited period)

 

8 – ACG Clinical Guideline: Management of Crohn’s Disease in Adults – The American Journal of Gastroenterology (free)

Commentary: New Crohn Disease Management Guidelines: Top Five Takeaways – Medscape (free registration required)

 

9 – Obesity Increases the Duration of Influenza A Virus Shedding in Adults – The Journal of Infectious Diseases (free)

Commentaries: Study suggests obesity may increase flu spread – CIDRAP (free) AND Beyond Disease Severity: The Impact of Obesity on Influenza A Virus Shedding – The Journal of Infectious Diseases (free) AND Study suggests obesity may also impact flu transmission, not just severity of illness – Infectious Diseases Society of America, via EurekAlert (free) AND Obesity extends duration of influenza A virus shedding – NIH News (free)

 

10 – Increasing tolerance of hospital Enterococcus faecium to handwash alcohols – Science Translational Medicine (link to abstract – $ for full-text)

Commentaries: Study finds increased alcohol tolerance in common hospital pathogen – CIDRAP (free) AND Superbugs now also becoming resistant to alcohol disinfectants – Reuters (free) AND Some Bacteria Are Becoming ‘More Tolerant’ Of Hand Sanitizers, Study Finds – NPR (free)

Researchers found that E faecium isolates collected in 2 Australian hospitals after 2009 were 10x more tolerant to alcohol than those collected before 2004, and that the date of isolation was a much better predictor of survival than the genotype” (via @CIDRAP_ASP see Tweet)

 

Thu, August 2 – 10 Stories of The Day!

2 Aug,2018

 

1 – Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults – New England Journal of Medicine (free)

Related Article: Safety and Side Effects of Rifampin versus Isoniazid in Children – New England Journal of Medicine (free)

Quick Take Video Summary: Rifampin or Isoniazid for Latent Tuberculosis (free)

Commentaries: New tuberculosis treatment could help tackle global epidemic – The Guardian (free) AND Rifampin Promising for Latent TB in Phase 3 Trials – Medscape (free registration required)

 

2 – Clinical Report: Physician’s Role in Coordinating Care of Hospitalized Children – American Academy of Pediatrics (free)

News Release: Report guides pediatricians in improving care coordination of hospitalized children – AAP News (free)

 

3 – Prospective Validation of the 0/1-h Algorithm for Early Diagnosis of Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Validation of ESC 0/1-h Algorithm for MI – American College of Cardiology (free) AND ESC Algorithm Safely Rules Out NSTEMI, But Caution May Be Warranted in the US – TCTMD (free)

Related Review: High-Sensitivity Cardiac Troponin in the Evaluation of Possible AMI – American College of Cardiology (free)

 

4 – Prospective Randomized Evaluation of Preoperative Angiotensin-Converting Enzyme Inhibition (PREOP-ACEI) – Journal of Hospital Medicine (free)

Commentary: Omitting ACE inhibitor before surgery reduced intraoperative hypotension, study finds – ACP Hospitalist (free)

 

5 – Cluster of presumptive Ebola cases in North Kivu in the Democratic Republic of the Congo – World Health Organization (free)

Commentaries: New Ebola outbreak declared in DRC a week after earlier one declared over – STAT (free) AND DRC confirms new Ebola cluster days after outbreak declared over – CIDRAP (free) AND Congo declares new Ebola outbreak in eastern province – Reuters (free) AND Deadly Ebola Strikes Anew, a Week After Previous Outbreak Was Extinguished – The New York Times (10 articles per month are free)

 

6 – Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline – Neurology (link to abstract – $ for full-text)

Commentary: People who frequently feel dizzy on standing ‘at future risk of dementia’ – NHS Choices (free)

Related Research: Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort – European Heart Journal (free)

 

7 – A Consensus Statement on acromegaly therapeutic outcomes – Nature Reviews Endocrinology (free)

Commentary: Consensus statement: optimizing acromegaly management – Univadis (free registration required)

 

8 – Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study – The BMJ (free)

Editorial: Relation between alcohol consumption in midlife and dementia in late life (free)

Commentaries: Expert reaction to long term abstinence and heavy drinking associated with dementia – Science Media Centre (free) AND Middle-aged non-drinkers may have ‘higher risk’ of dementia – The Guardian (free)

 

9 – Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis – JAMA Cardiology (free for a limited period)

Author Interview: Efficacy and Safety of Further Lowering of LDL Cholesterol in Patients Starting With Very Low Levels (free)

 

10 – MRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men – Radiology (free for a limited period)

Commentaries: Soccer Heading May Be Riskier for Female Players – RSNA (free) AND Heading May Be Riskier For Female Soccer Players Than Males – NPR (free)

 

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