Open access


Fri, October 19 – 10 Stories of The Day!

19 Oct,2018


1 – Pre-eclampsia and risk of dementia later in life: nationwide cohort study – The BMJ (free)

Editorial: Pre-eclampsia and the brain (free)

Commentaries: Pre-eclampsia linked to raised risk of vascular dementia – OnMedica (free) AND Pre-eclampsia linked to an increased risk of dementia later in life – The BMJ (free)


2 – Perspective: To Prevent Cardiovascular Disease, Pay Attention to Pregnancy Complications – JAMA (free for a limited period)

Related: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease (link to abstract and commentaries)


3 – Enhanced Recovery in Surgical Intensive Care: A Review – Frontiers in Medicine (free)


4 – Review: Newer technologies for detection of atrial fibrillation – The BMJ (free for a limited period)


5 – Effect of Cricoid Pressure Compared With a Sham Procedure in the Rapid Sequence Induction of Anesthesia: The IRIS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentaries: Is 30 Newtons of Prevention Worth a Pound of a Cure?—Cricoid Pressure – JAMA Surgery (free for a limited period) AND The Case of the Inferior Superiority – EMNerd (free)


6 – US FDA Breast Implant Postapproval Studies: Long-term Outcomes in 99,993 Patients – Annals of Surgery (free)

Commentary: Long-term safety of silicone breast implants still unclear – Reuters (free)


7 – See It, Want It, Buy It, Eat It – Cancer Research UK (free PDF)

Commentaries: Time spent by children online linked to requests for junk food – University of Liverpool (free) AND Does TV and internet advertising feed children’s junk food habits? – NHS Choices (free)


8 – Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study – The Lancet (link to abstract – $ for full-text)

Commentary: AI: Deep Learning Algorithms Can Detect Critical Head CT Findings – MedicalResearch.com (free)


9 – Antidepressant withdrawal: reviewing the paper behind the headlines – The Mental Elf (free) (via @AllenFrancesMD)

Original Systematic Review: Antidepressant Withdrawal Effects (free article and commentaries)

“Last week a new review said: – Over half of people taking antidepressants experience withdrawal symptoms – These symptoms are severe in over half of cases. The press had a field day! Our blog today by @J_F_Hayes and @sameerjauhar offers a different view” (via @Mental_Elf see Tweet)


10 – Association of Aspirin With Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty Compared With Other Anticoagulants: A Noninferiority Analysis – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: More Research Supports Use of Aspirin Alone to Prevent VTE After Knee Replacement Surgery – TCTMD (free) AND Aspirin Noninferior to Other Anticoagulants in Knee Arthroplasty – Journal Watch (free)

Related Randomized Trial: Aspirin Starting Five Days After Hip or Knee Arthroplasty for VTE Prophylaxis (link to abstract, video summary and commentary)


Thu, October 18 – 10 Stories of The Day!

18 Oct,2018


1 – Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories – The Lancet (free)

Commentaries: Major strides in forecasting future health – The Lancet (free) AND Why Life Expectancy in 2040 Could Be Lower Than It Is Today – LiveScience (free) AND How healthy will we be in 2040? – Institute for Health Metrics and Evaluation (free)


2 – Acute Flaccid Myelitis Investigation Page – Centers for Disease Control and Prevention (free)

Commentaries: CDC, partners probe 127 polio-like cases in 22 states – CIDRAP (free) AND CDC Investigates Cases Of Rare Neurological ‘Mystery Illness’ In Kids – NPR (free) AND Acute Flaccid Myelitis Cases Confirmed in 22 States Physician’s First Watch (free) AND CDC expresses concern over mysterious surge in polio-like paralysis cases – STAT (free)


3 – Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

Related: Cardiovascular Toxicity in Cancer Survivors (free review and guidelines) AND Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors (link to abstract and commentaries) AND The cumulative burden of surviving childhood cancer (link to abstract and commentaries) AND Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood (free study and commentaries) AND Endocrine Disorders in Survivors of Childhood Cancer (free guideline and commentaries)


4 – Australia is responding to the complex challenge of overdiagnosis – The Medical Journal of Australia (free for 7 days)

Commentaries: Overdiagnosis: a deep cultural problem – MJA InSight (free) AND Overdiagnosis is harming patients and action is required, says chief medical officer – The Sidney Morning Herald (free)

Related: Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF)


5 – Podcast: #119 Nutrition Pearls, Heart Health, Bacon – Curbsiders Internal Medicine Podcast (free audio and summary)


6 – Sarcopenia: revised European consensus on definition and diagnosis – Age and Ageing (free)


7 – Position Statement: Guidelines for vitamin K prophylaxis in newborns: A joint statement of the Canadian Paediatric Society and the College of Family Physicians of Canada – Canadian Family Physician (free)


8 – Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology – Cochrane Library (free for a limited period)

Summary: Progestogen for preventing miscarriage – Cochrane Library (free)


9 – Deep Learning to Distinguish Recalled but Benign Mammography Images in Breast Cancer Screening – Clinical Cancer Research (free PDF)

Commentaries: Study Finds Deep Learning Can Distinguish Recalled-Benign Mammogram Images From Malignant and Negative Cases – The ASCO Post (free) AND AI distinguishes false-positive mammograms from malignant, negative mammograms – Radiology Business (free) AND Deep learning can distinguish recalled-benign mammograms from malignant and negative images – eCancer News (free)


10 – Hospital Readmission Following Takotsubo Syndrome – European Heart Journal – Quality of Care and Clinical Outcomes (link to abstract – $ for full-text)

Commentaries: Takotsubo Syndrome Linked to Heart Failure Admissions and Mortality Risk in Nationwide Study – TCTMD (free) AND Avoiding Broken-Heart Syndrome Readmissions – MedPage Today (free registration required)

Related: International Registry: Long-Term Prognosis of Patients With Takotsubo Syndrome (link to abstract and commentaries) International Expert Consensus Document on Takotsubo Syndrome (free guideline) AND Review: Takotsubo Syndrome (free reviews)


Wed, October 17 – 10 Stories of The Day!

17 Oct,2018


1 – Association Between Bariatric Surgery and Macrovascular Disease Outcomes in Patients With Type 2 Diabetes and Severe Obesity – JAMA (link to abstract – $ for full-text)

Video Summary: How Does Bariatric Surgery Compare With Medical Care for Reducing Cardiovascular Disease in Patients With Type 2 Diabetes? (free)

Commentary: Obesity surgery may lower heart attack danger in diabetics – Associated Press (free)


2 – Perspective: The New Age of Patient Autonomy: Implications for the Patient-Physician Relationship – JAMA (free for a limited period) (via @EricTopol)


3 – Perspective: What should we stop doing in the ICU? – ICU Management & Practice (free)


4 – Perspective: I hate guidelines (but they can improve and you can help) – First10Em (free) (via @srrezaie)


5 – Review: Treatments targeting inotropy – European Heart Journal (free)


6 – Review: Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies – Clinical and Applied Thrombosis/Hemostasis (free)

Source: Critical Care Reviews Newsletter


7 – Researcher Requests for Inappropriate Analysis and Reporting: A U.S. Survey of Consulting Biostatisticians – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: When scientists want their data fudged and why you should care – CBC (free)


8 – Heart disease used to be an ailment of the rich. But it’s now striking the world’s poor. – VOX (free)

“In 2016, an estimated 1 million people died of HIV/AIDS, 445,000 people died of malaria, and 1.7 million died of tuberculosis. Nearly 18 million died of heart disease. And more than three-quarters of those deaths occurred in the developing world.”


9 – Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems – Cochrane Library (free for a limited period)

Summary: Calcium supplementation during pregnancy for preventing blood pressure disorders and related problems – Cochrane Library (free)


10 – Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Study: Antibiotics for bacterial vaginosis don’t cut preterm birth risk – CIDRAP (free)


Tue, October 16 – 10 Stories of The Day!

16 Oct,2018


1 – Attention deficit hyperactivity disorder late birthdate effect common in both high and low prescribing international jurisdictions: systematic review – The Journal of Child Psychology and Psychiatry (free)

Commentary: Global study finds youngest in class more likely to be diagnosed with ADHD – University of Adelaide (free)

“Youngest kids in class much more likely get ADHD diagnosis than oldest. Bad News: Simple immaturity now turned into mental illness & treated with meds” (via @AllenFrancesMD see Tweet)


2 – Many Analysts, One Data Set: Making Transparent How Variations in Analytic Choices Affect Results – Advances in Methods and Practices in Psychological Science (free) (via @f_g_zampieri)

“This is one of most important studies published this century. 29 teams used same data set to address same research question; estimated effect sizes ranged from 0.89 to 2.93 in odds-ratio units. Dramatic implications for observational research.” (via @hmkyale see Tweet)


3 – WHO Statement: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

Related: DR Congo: managing Ebola virus in war – The Lancet (free) AND Ebola experts from CDC were pulled from outbreak zone amid security concern – STAT (free) AND Ebola showed up in a war zone. It’s not going well – VOX (free) AND Experts Said A War Zone Ebola Outbreak Would Be A Nightmare. It’s Been Even Worse – HuffPost (free) AND DRC Ebola cases top 200 as security problems fuel the spike – CIDRAP (free)


4 – A pandemic killing tens of millions of people is a real possibility — and we are not prepared for it – VOX (free)

Related: Innovation for Pandemics (free perspectives and video on the subject)


5 – Ann Robinson’s research reviews, 15 October 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.


6 – Demystifying serotonin syndrome (or serotonin toxicity) – Canadian Family Physician (free)


7 – Approach to the detection and management of chronic kidney disease: What primary care providers need to know – Canadian Family Physician (free)


8 – Oliguria in critically ill patients: a narrative review – Journal of Nephrology (free)

Source: Critical Care Reviews Newsletter


9 – β-Blocker Use in Pregnancy and the Risk for Congenital Malformations: An International Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Beta-Blocker Use in First Trimester Seems Safe – Physician’s First Watch (free) AND Beta-blocker Use in Pregnancy Doesn’t Up Birth Defect Risk, Study Suggests – TCTMD (free)


10 – Identity inference of genomic data using long-range familial searches – Science (free for a limited period)

Commentaries: Most White Americans’ DNA Can Be Identified Through Genealogy Databases – The New York Times (10 articles per month are free) AND How an Unlikely Family History Website Transformed Cold Case Investigations – The New York Times (10 articles per month are free) AND ‘We are increasingly exposed’: New studies show how easy it is to identify people using genetic databases – STAT (free) AND Supercharged crime-scene DNA analysis sparks privacy concerns – Nature (free)


Mon, October 15 – 10 Stories of The Day!

15 Oct,2018


1 – WHO recommendations: non-clinical interventions to reduce unnecessary caesarean sections – World Health Organization (free PDF)

News Release: New WHO guidance on non-clinical interventions specifically designed to reduce unnecessary caesarean sections (free)

Related Cochrane Review: Non‐clinical interventions for reducing unnecessary caesarean section (free review and summary)


2 – Series: Optimising caesarean section use – The Lancet (free articles and commentaries, registration required)

Commentaries: Caesarean section use has almost doubled globally since 2000 – The Lancet (free) AND C-section births rise rapidly to more than 20 percent worldwide – Reuters (free) AND Rate Of C-Sections Is Rising At An ‘Alarming’ Rate, Report Says – NPR (free) AND C-section deliveries nearly doubled worldwide since 2000, study finds – CNN (free) AND C-section births surge to ‘alarming’ rates worldwide – study – BBC (free)


3 – A blueprint for the primary prevention of cancer: Targeting established, modifiable risk factors – CA: A Cancer Journal for Clinicians (free)

Commentary: Comprehensive report says tobacco control must be highest priority in cancer control – American Cancer Society (free)


4 – Analysis: Treatment burden should be included in clinical practice guidelines – The BMJ (free for a limited period)


5 – Opinion: Professional Societies Should Abstain From Authorship of Guidelines and Disease Definition Statements – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Professional Societies, Clinical Specialists, and Guidelines – Circulation: Cardiovascular Quality and Outcomes (free) AND Turn Cardiology Guidelines Over to Outsiders – MedPage Today (free registration required)

John Ioannidis, MD. “questioned whether cardiovascular guidelines “homogenize biased, collective, and organized ignorance” through use of predominantly “insider” experts as authors.” (from MedPage Today)


6 – Diagnosis and management of non-dialysis chronic kidney disease in ambulatory care: a systematic review of clinical practice guidelines – BMC Nephrology (free)


7 – KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea – Allergy, Asthma & Immunology Research (free)

Related: Managing Patients with Chronic Cough (free CHEST guidelines on the subject)


8 – Supplement: Digital Health and Health Systems of the Future – Global Health: Science and Practice (free articles)

Source: International Health Policies Newsletter


9 – Association of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery With Surgical Site Infection: A Network Meta-analysis – JAMA Network Open (free)

Invited Commentary: When Will the Surgical Community Acknowledge the Evidence Regarding Prophylaxis With Oral Antibiotics for Scheduled Colorectal Operations? (free)

Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery. Once again the combination of oral antibiotic and oral mechanical cathartic bowel preparation yields the lowest rates of surgical site infections” (via @SWexner see Tweet)


10 – Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings – JAMA Network Open (free)

Editorial: The FDA and Adulterated Supplements—Dereliction of Duty – JAMA Network Open (free)

Commentaries: Nearly 800 dietary supplements contained unapproved drug ingredients, study finds – CNN (free) AND No Wonder It Works So Well – NPR (free) AND Hundreds of Dietary Supplements Are Tainted with Prescription Drugs – Scientific American (free) AND Hundreds of health, weight loss products contain unapproved ingredients: Study – UPI (free) AND Some dietary supplements contain potentially harmful drugs – Reuters (free)


Fri, October 12 – 10 Stories of The Day!

12 Oct,2018


1 – Review: What treatments are effective for common cold in adults and children? – The BMJ (free review and infographic)

Commentaries: What works for treating children’s colds? – BBC (free) AND Doctors should steer young children away from decongestants – OnMedica (free)


2 – How To Prevent Brain-Sapping Delirium In The ICU – NPR (free text and podcast)

Related: ABCDEF Bundle – Society of Critical Care Medicine (free resource) AND The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families – Critical Care Medicine (free)


3 – Correspondence: Real-Time Patient–Provider Video Telemedicine Integrated with Clinical Care – New England Journal of Medicine (free)


4 – Perspective: The approach to predictive medicine that is taking genomics research by storm – Nature (free)

“Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial.”


5 – Review: Venous thromboembolism prophylaxis may cause more harm than benefit: an evidence-based analysis of Canadian and international guidelines – Thrombosis Journal (free) (via @amtejani)


6 – Review: A New Vaccine for Shingles – Therapeutics Initiative (free)

“Need to vaccinate 31 people to prevent one instance of HZ; Need to vaccinate 358 people to prevent one instance on post herpetic neuralgia” (via @amtejani)


7 – Environmental Noise Guidelines for the European Region (2018) – World Health Organization (free PDF)

Commentary: Noise: The other pollution hurting our health – CNN (free)


8 – Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology – Clinical and Translational Oncology (free)


9 – Effectiveness of the Stand More AT (SMArT) Work intervention: cluster randomised controlled trial – The BMJ (free)

Editorial: Reducing sedentary behaviour in the workplace (free)

Commentaries: Standing-desk workers ‘less tired, more engaged’ – BBC (free) AND Sit-stand desks may improve job performance, psychological health – UPI (free)


10 – Association of Unrecognized Myocardial Infarction With Long-term Outcomes in Community-Dwelling Older Adults: The ICELAND MI Study – JAMA (free for a limited period)

Commentaries: Silent Infarcts Have Similar Mortality Over 10 Years as Clinically Recognized MI – TCTMD (free) AND Association of Unrecognized MI With Long-Term Outcomes – American College of Cardiology (free)

Related Study: Silent Myocardial Infarction and Long-Term Risk of Heart Failure (link to abstract and commentaries)


Thu, October 11 – 10 Stories of The Day!

11 Oct,2018


1 – The Lancet Commission on global mental health and sustainable development (free registration required)

Commentaries: Mental health crisis could cost the world $16 trillion by 2030 – Reuters (free) AND Mental health disorders will cause ‘monumental suffering’ and cost £12 TRILLION a year worldwide by 2030 – The Daily Mail (free) AND World in mental health crisis of ‘monumental suffering’, say experts – The Guardian (free)


2 – Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update – Canadian Medical Association Journal (free)


3 – Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis – New England Journal of Medicine (link to abstract – $ for full-text)

Video Summary: Renal-Replacement Therapy for AKI (free)

Commentary: Is Kidney Dialysis Always Needed When Septic Shock Strikes? – HealthDay (free)

“Trial comparing early vs. delayed strategies of renal-replacement therapy in patients with early-stage septic shock who had severe acute kidney injury finds no significant between-group difference in overall mortality at 90 days.” (via @NEJM see Tweet)


4 – Effect of Immediate vs Delayed Pushing on Rates of Spontaneous Vaginal Delivery Among Nulliparous Women Receiving Neuraxial Analgesia: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video Summary: Immediate vs Delayed Pushing During Second Stage of Labor (free)

Commentaries: When Giving Birth For The First Time, Push Away – NPR (free) AND In childbirth, when to begin pushing does not affect C-section rates – Washington University in St. Louis (free) AND Vaginal delivery not affected by delayed pushing, study says – UPI (free)


5 – Review: Management of severe acute exacerbations of COPD: an updated narrative review – Multidisciplinary Respiratory Medicine (free)


6 – Review: An update on the use of inhaled therapy in COPD – Clinical Medicine (free)


7 – Review: What is the significance of monoclonal gammopathy of undetermined significance? – Clinical Medicine (free)


8 – Ghost authorship haunts industry-funded clinical trials – Nature (free)

Original Article: Collaboration Between Academics and Industry in Clinical Trials (free study and commentaries)


9 – Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts – The BMJ (free)

Editorial: The role of diet in serum urate concentration (free)

Commentary: Diet Might Play Less of a Role in Gout Than Previously Thought – Physician’s First Watch (free)


10 – Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin – BMJ Case Reports (free)

Commentaries: Planned intermittent fasting may help reverse type 2 diabetes, suggest doctors – BMJ (free) AND Therapeutic Fasting Could Be an Alternative to Insulin for Some Diabetes Patients – Physician’s First Watch (free)


Wed, October 10 – 10 Stories of The Day!

10 Oct,2018


1 – Cluster Randomized Clinical Trial of FAITH (Faith-Based Approaches in the Treatment of Hypertension) in Blacks – Circulation: Cardiovascular Quality and Outcomes (free)

Editorial: Of Barbershops and Churches: Can Community-Based Interventions Improve Cardiovascular Risk in High-Risk Patients? (free)

Commentaries: Faith-based approach to changing lifestyle lowers blood pressure – AHA Newsroom (free) AND How church communities can help lower African-Americans’ blood pressure – CNN (free) AND Church-Based Lifestyle Intervention Shows Promise for Lowering BP in Hypertensive African-Americans – TCTMD (free)

Related Study: Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops (free study and commentaries)


2 – Fluoroquinolone and quinolone antibiotics: PRAC recommends new restrictions on use following review of disabling and potentially long-lasting side effects – European Medicines Agency (free)

Commentaries: EMA committee recommends restrictions on fluoroquinolone, quinolone antibiotics – Reuters (free) AND PRAC Recommends Restrictions on Fluoroquinolone, Quinolones – Medscape (free registration required)

Related FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions (free statement and commentaries)


3 – Evidence synthesis for health policy and systems: a methods guide – World Health Organization (free PDF) (via @trishgreenhalgh)


4 – Non-celiac gluten/wheat sensitivity (NCGS)—a currently undefined disorder without validated diagnostic criteria and of unknown prevalence – Position statement of the task force on food allergy of the German Society of Allergology and Clinical Immunology (DGAKI) (free)


5 – Review: Managing the Patient with Heart Failure in the Emergency Department – European Heart Journal (free) (via @gonzaeperez)


6 – Review: Office approach to small fiber neuropathy – Cleveland Clinic Journal of Medicine (free)


7 – Review: Bicuspid aortic valve: Basics and beyond – Cleveland Clinic Journal of Medicine (free)


8 – Nine ways research could save the NHS money – NHS Dissemination Centre (free)

New infographic series with selected NIHR Signals covering a range of treatments and initiatives that are cost effective.


9 – 800,000 people kill themselves every year. What can we do? – The Guardian (free) (via @onisillos)

Related Guidelines: Preventing suicide: A community engagement toolkit – World Health Organization (free PDF) AND Preventing suicide in community and custodial settings – National Institute for Health and Care Excellence (free)

“In too many places mental health support services are non-existent and those with treatable conditions are criminalized. Bold action is long overdue”


10 – Electronic cigarette explosion and burn injuries, US Emergency Departments 2015–2017 – Tobacco Control (link to abstract – $ for full-text)

Commentaries: E-cigarette explosion and burn injuries have been underestimated by federal agencies – George Mason University (free) AND Study: E-Cigarette Injuries Drastically Underestimated – MedPage Today (free registration required)


Tue, October 9 – 10 Stories of The Day!

9 Oct,2018


1 – Level 3 guideline on the treatment of patients with severe/multiple injuries – German Trauma Society (free)

News Release: The updated German “Polytrauma – Guideline”: an extensive literature evaluation and treatment recommendation for the care of the critically injured patient (free)

Source: Critical Care Reviews Newsletter


2 – ESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free)

Source: Critical Care Reviews Newsletter


3 – Non‐clinical interventions for reducing unnecessary caesarean section – Cochrane Library (free for a limited period)

Summary: Non-clinical interventions for reducing unnecessary caesarean section (free)


4 – Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women – Cochrane Library (free)

Based on the data available, we can be confident that pelvic floor muscle training can cure or improve symptoms of stress urinary incontinence and all other types of urinary incontinence”


5 – Perspective: The Name of the Dog – New England Journal of Medicine (free)

“During morning rounds, I had presented a patient who was admitted for chest pain after walking his dog. My attending had asked, ‘What was the name of his dog?’ ” (via @fischmd see Tweet)


6 – Zackary Berger’s journal reviews, 8 October 2018 – The BMJ Opinion (free)

Zackary Berger reviews the latest research from the top medical journals.


7 – Last Month in Oncology with Dr. Bishal Gyawali: September 2018 – eCancer News (free)


8 – Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention (via @EricTopol)


9 – Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial – The BMJ (free)

“Laparoscopic cholecystectomy compared with percutaneous catheter drainage reduced the rate of major complications in high risk patients with acute cholecystitis.”


10 – Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statin Benefits: Yes for CVD but No for Everything Else, Says New Review – TCTMD (free) AND Statins’ benefits beyond heart health aren’t clear-cut, analysis says – CNN (free)


Mon, October 8 – 10 Stories of The Day!

8 Oct,2018


1 – Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetes Care (free PDF)

Commentaries: New Consensus Report from the American Diabetes Association® (ADA) and the European Association for the Study of Diabetes (EASD) Calls for Paradigm Shift to Patient-Centered Care for Type 2 Diabetes – American Diabetes Association (free) AND New EASD-ADA consensus guidelines on managing hyperglycaemia in type 2 diabetes launched at EASD meeting – Diabetologia (free)

Related Guidelines: WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings (free guideline and commentaries) AND Pharmacologic Glycemic Management of Type 2 Diabetes in Adults – Canadian Journal of Diabetes (free) AND ADA 2018 Standards of Medical Care in Diabetes (free guideline and commentaries) AND ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes (free guideline and commentaries)


2 – Supplement: ESMO Updated Clinical Practice Guidelines – European Society of Medical Oncology (free)


3 – Perspective: What the tests don’t show – The Washington Post (a few articles per month are free)

“Many doctors are surprisingly bad at reading test results and/or fail to grasp how false positives work. This is putting patients at risk” (via @pash22 see Tweet)


4 – Perspective: Why Employers Should Stop Giving Away Snacks – Pacific Standart (free)

Source: Global Health NOW Newsletter


5 – Outpatient antibiotics widely prescribed without an infection diagnosis – CIDRAP (free)

Related Commentary: Study Finds Almost Half of Antibiotic Prescriptions Written Without a Diagnosis – Pharmacy Times (free)


6 – Review: The Diagnosis and Treatment of Anxiety Disorders – Deutsches Ärzteblatt international (free)


7 – Review: Cardiovascular disease and COPD: dangerous liaisons? – European Respiratory Review (free)


8 – COPD Guidelines: A Review of the 2018 GOLD Report – Mayo Clinic Proceedings (free)

Related: Highlights from the New GOLD COPD Guidelines (free guideline and commentaries)


9 – Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial – The Lancet (free)

Commentaries: Enlarging the loop: closed-loop insulin delivery for type 1 diabetes – The Lancet (free) AND Hybrid Closed Loop System Aid for Tighter Glucose Control – MedPage Today (free registration required)


10 – Effectiveness of Online vs In-Person Care for Adults With Psoriasis: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Treating psoriasis in the future could be as easy as going online – USC News (free)


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