Open access


Tue, December 11 – 10 Stories of The Day!

11 Dec,2018


1 – Manual: Preventing surgical site infections: implementation approaches for evidence-based recommendations – World Health Organization (free PDF) (via @onisillos)


2 – Recommendations on screening for breast cancer in women aged 40–74 years who are not at increased risk for breast cancer – Canadian Medical Association Journal (free)

Summary: Breast Cancer Update (2018) – Canadian Task Force on Preventive Health Care (free)

News Release: Breast cancer screening: New emphasis on shared decision-making between women and their doctors (free)

See Also: Infographics for Shared Decision-Making (free)


3 – The Association of Coloproctology of Great Britain and Ireland consensus guidelines in surgery for inflammatory bowel disease – Colorectal Disease (free)


4 – Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) (via @gonzaeperez)


5 – Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis – PLOS One (free)


6 – Review: Management Options for Irritable Bowel Syndrome – Mayo Clinic Proceedings (free)


7 – What These Medical Journals Don’t Reveal: Top Doctors’ Ties to Industry – The New York Times (10 articles per month are free)


8 – Cochrane Special Collections: Diagnosing skin cancer (free articles)

News Release: Cochrane Library Special Collection: Diagnosing skin cancer (free)


9 – Patient safety after implementation of a coproduced family centered communication programme: multicenter before and after intervention study – The BMJ (free)

Commentaries: Ensure that the family’s voice is heard first and last, and in their own words – The BMJ Opinion (free) AND Improving patient safety? Ask the patient – The BMJ Opinion (free) AND A new way to curb harmful medical errors: talk more to patients and families – STAT (free)


10 – Ultrarestrictive Opioid Prescription Protocol for Pain Management After Gynecologic and Abdominal Surgery – JAMA Network Open (free)

Commentaries: Striving for Evidence-Based Postoperative Opioid Prescribing While Optimizing Perioperative Pain Management—Shifting to Conservative Prescribing – JAMA Network Open (free) AND Opioid Prescriptions Can Be Drastically Reduced After Surgery with No Increase in Pain, Study Shows – Roswell Park (free)


Mon, December 10 – 10 Stories of The Day!

10 Dec,2018


1 – Guideline: Chronic obstructive pulmonary disease (acute exacerbation): antimicrobial prescribing – National Institute for Health and Care Excellence (free)

Commentary: GPs should consider restricting antibiotics for COPD – OnMedica (free)


2 – Guideline: Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)


3 – Guideline: Post-traumatic stress disorder – National Institute for Health and Care Excellence (free)


4 – Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018 – Japanese Society of Nephrology (free)


5 – Quantifying the benefits and harms of various preventive health activities – Australian Journal of General Practice (free) (via @PaulGlasziou)


6 – Dr. Lisa Schwartz, Critic of Medical Excess, Is Dead at 55 – The New York Times (10 articles per month are free)


7 – Critical review of the evidence underlying management of glucocorticoid-induced hyperglycaemia – European Journal of Endocrinology (free)


8 – Prevalence of and Factors Associated With Patient Nondisclosure of Medically Relevant Information to Clinicians – JAMA Network Open (free)

Commentaries: Threats to the Validity of the Clinical Interview: Can Anything Be Done? – JAMA Network Open (free) AND Patients often withhold relevant information from doctors – Reuters (free) AND Most Patients Have Held Back the Truth From Doctors, JAMA Results Show – AJMC (free) AND Why patients lie to their doctors – University of Utah Health (free) AND Majority of Patients Withhold Important Information From Their Health Care Providers – MedicalResearch.com (free)


9 – The UCL–Lancet Commission on Migration and Health: the health of a world on the move (free articles – registration required)

Commentaries: Harmful myths about migration and health used to justify policies of exclusion are unfounded – London School of Hygiene & Tropical Medicine (free) AND Report: Facts About Migrants Don’t Always Match What The Headlines Say – NPR (free) AND Myths about migrants spreading disease ‘inform hostile policies’ – The Guardian (free)


10 – Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial – The Lancet (free)

Commentaries: Fluoxetine and recovery after stroke – The Lancet (free) AND Fluoxetine (Prozac) Did Not Reduce Risk of Depression After Stroke, But Did Raise Risk of Fractures – MedicalResearch.com (free) AND Common antidepressant does not aid stroke recovery, study finds – University of Edinburgh (free)


Fri, December 7 – 10 Stories of The Day!

7 Dec,2018


1 – 2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment – Journal of the American College of Cardiology (free)

Summary: 2018 ACC Decision Pathway on Tobacco Cessation Treatment – American College of Cardiology (free)


2 – Anesthesia interventions that alter perioperative mortality: a scoping review – Systematic Review (free)


3 – Apixaban to Prevent Venous Thromboembolism in Patients with Cancer – New England Journal of Medicine (free)

Commentary: NOACs Significantly Curb Risk of VTE in Cancer Patients – TCTMD (free)


4 – 2018 recommendations for the management of community acquired pneumonia – Jornal Brasileiro de Pneumologia (free PDF)

Related Guideline: Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence (free)


5 – Review: Assessment and initial management of acute undifferentiated fever in tropical and subtropical regions – The BMJ (free for a limited period)


6 – Review: Diaphragmatic dysfunction – Pulmonology (free)


7 – Review: Examination of the Patient with Dizziness or Imbalance – Medical Clinics of North America (free)


8 – Perspective: Risk-Reducing Mastectomy in BRCA1 and BRCA2 Mutation Carriers: A Complex Discussion – JAMA (free for a limited period)


9 – China backs bold plan to tear down journal paywalls – Nature (free)

Related: Europe’s Bold Open-Access Plan Detailed (free report and commentaries)


10 – Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker – Nature Communications (free)

Commentaries: One test to diagnose them all: researchers exploit cancers’ unique DNA signature – The Conversation (free) AND Nano-signature discovery could revolutionise cancer diagnosis – University of Queensland (free) AND ‘Universal fingerprint’ in cancer DNA points to potential blood test. But it’s not ready for patients – Cancer Research UK (free) AND Holy grail cancer test? Hold on. Here’s what you need to know – HealthNewsReview (free)


Thu, December 6 – 10 Stories of The Day!

6 Dec,2018


1 – Systematic Review: What are the most common conditions in primary care? – Canadian Family Physician (free)


2 – Perspective: Whole-Fat or Nonfat Dairy? The Debate Continues – JAMA (free for a limited period)


3 – Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility – The Lancet (link to abstract – $ for full-text)

Commentaries: For the first time, a baby is born via a uterus transplant from a deceased donor – STAT (free) AND Mother gives birth with uterus from deceased donor – OnMedica (free) AND Expert reaction to first baby born by uterus transplant from a deceased donor – Science Media Centre (free) AND First baby born after deceased womb transplant – BBC (free)


4 – 2018 Korean Guideline of Atrial Fibrillation Management – Korean Circulatory Journal (free)

Related Guidelines: 2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation (free) AND 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (free)


5 – Nurse staffing, nursing assistants and hospital mortality: retrospective longitudinal cohort study – BMJ Quality & Safety (free)

Commentaries: Lack of nurses linked to increased risk of patient death – OnMedica (free) AND Low Nurse Staffing Increases Risk for Inpatient Death – Medscape (free registration required)


6 – Caring for the critically ill patients over 80: a narrative review – Annals  of Intensive Care (free)


7 – Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention – Current Treatment Options in Cardiovascular Medicine (free)


8 – Podcast: Delirium: Prevention, Diagnosis, and Treatment – JAMA (free)


9 – Association of estimated sleep duration and naps with mortality and cardiovascular events: a study of 116 632 people from 21 countries – European Heart Journal (free)

News Release: Too much or too little sleep linked to increased risk of cardiovascular disease and death – European Society of Cardiology (free)

Editorial: Sleep and cardiovascular risk: how much is too much of a good thing? (free)


10 – Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis – JAMA Network Open (free)

Commentaries: Identifying Risk of Psychosis in a Primary Care Setting – JAMA Network Open (free) AND Spotting patients at risk for psychosis: 12 high-risk symptoms – Univadis (free registration required)


Wed, December 5 – 10 Stories of The Day!

5 Dec,2018


1 – Finding the Balance Between Benefits and Harms When Using Statins for Primary Prevention of Cardiovascular Disease: A Modeling Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statins may be significantly overprescribed for primary prevention, computer model suggests – ACP Internist (free) AND Benefits of Statins Only Exceed Harms at Higher 10-Year Risk Thresholds, Study Suggests – TCTMD (free) AND Higher Risk Thresholds May Be Needed for Starting Statins for Primary CVD Prevention, Study Suggests – NEJM Journal Watch (free) AND Statins are being overprescribed, study suggests – OnMedica (free)


2 – The Ethics of Heritable Genome Editing: New Considerations in a Controversial Area – JAMA (free for a limited period)

Related: WHO looks at standards in ‘uncharted water’ of gene editing – Reuters (free) AND The CRISPR Baby Scandal Gets Worse by the Day – The Atlantic (free) AND We need a temporary moratorium on using gene editing to create babies – STAT (free) AND Is the CRISPR baby controversy the start of a terrifying new chapter in gene editing? – VOX (free) AND First CRISPR babies: six questions that remain – Nature (free) AND ‘I feel an obligation to be balanced.’ Noted biologist comes to defense of gene editing babies – Science (free)


3 – Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice – International Journal of Endocrinology (free)

Commentary: Fasting for lab tests isn’t good for patients with diabetes – Michigan State University (free)


4 – Last Month in Oncology with Dr. Bishal Gyawali: November 2018 – eCancer News (free)


5 – Review: Confounders of severe asthma: diagnoses to consider when asthma symptoms persist despite optimal therapy – World Allergy Organization Journal (free)


6 – Perspective: Potential Risks and Benefits of Mental Health Screening of Physicians – JAMA (free for a limited period)


7 – Perspective: Why the world is becoming more allergic to food – BBC (free)


8 – Clinical validation of a risk scale for serious outcomes among patients with chronic obstructive pulmonary disease managed in the emergency department – Canadian Medical Association Journal (free)

News Release: Tool identifies which patients with COPD are at risk of death, serious complications (free)

Commentary: Tool quickly identifies risk for deadly COPD complications – UPI (free)


9 – Predictors of dementia misclassification when using brief cognitive assessments – Neurology (free PDF)

Commentary: Study Finds Biases in Widely Used Dementia Identification Tests – University of Exeter (free) AND Primary Care Tests Flunk for Classifying Dementia – MedPage Today (free registration required) AND Brief Cognitive Exams Commonly Misdiagnose Dementia – NEJM Journal Watch (free)


10 – Body-weight fluctuation and incident diabetes mellitus, cardiovascular disease, and mortality: a 16-year prospective cohort study – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentaries: Weight cycling is associated with a higher risk of death – The Endocrine Society (free) AND Study: Yo-yo diets can increase death risk – UPI (free)


Tue, December 4 – 10 Stories of The Day!

4 Dec,2018


1 – Why the HIV epidemic is not over – World Health Organization (free)


2 – Clinical Report: Selecting Appropriate Toys for Young Children in the Digital Era – American Academy of Pediatrics (free)

News Release: Best toys for children’s development? Hint: They are not electronic or costly – AAP News (free)

Commentaries: AAP Offer Toy Tips for Parents and Clinicians in the Digital Age – NEJM Journal Watch (free) AND Empty boxes top high-tech toys on doctor-recommended list – Associated Press (free)


3 – Perspective: Why Hospitals Should Let You Sleep – The New York Times (10 articles per month are free)

“Frequent disruptions are more than just annoying for patients. They can also cause harm.”


4 – Podcast: #128 Aspirin Overhyped and Overused – The Curbsiders Internal Medicine Podcast (free)


5 – Editorial: Focus on randomised clinical trials – Intensive Care Medicine (free PDF) (via @CritCareReviews)

Related: What should we stop doing in the ICU? – ICU Management & Practice (free)

Their results add to what appears to be a constant theme in critical care, ‘less is more’ based on RCT results”


6 – Alex Nowbar’s weekly research reviews, 3 December 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.


7 – Interpreting the Athlete’s ECG: Current State and Future Perspectives – Current Treatment Options in Cardiovascular Medicine (free)


8 – Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Natriuretic peptide-guided therapy falls flat in improving HFrEF outcomes – Cardiovascular Business (free) AND Quality-of-Life Outcomes With Natriuretic Peptide-Guided Therapy for Heart Failure – Cardiology Advisor (free)


9 – Clinical practice guidelines for older people with multimorbidity and life-limiting illness: what are the implications for deprescribing? – Therapeutic Advances in Drug Safety (free)


10 – Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis – The BMJ (free)

Commentaries: Joanna Crocker: Time to embrace patient involvement in clinical trials? – The BMJ Opinion (free) AND “Researchers don’t know what they’re missing”—the impact of patient involvement in research – The BMJ Opinion (free) AND Impact of PPI in clinical trials – University of Oxford (free)


Mon, December 3 – 10 Stories of The Day!

3 Dec,2018


1 – Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa – New England Journal of Medicine (free)

Commentaries: Studies Show Improved Sickle Cell Disease Outcomes Worldwide – American Society of Hematology (free) AND ASH 2018: Large Single-Arm Trial of Hydroxyurea for Sickle Cell Anemia in Sub-Saharan Africa – The ASCO Post (free) AND Sickle cell anemia treatment safely lowers disease burden in African children – Cincinnati Children’s Hospital Medical Center (free) AND ‘From Nothing to Gangbusters’: A Treatment for Sickle-Cell Disease Proves Effective in Africa – New England Journal of Medicine (10 articles per month are free)


2 – 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis – Arthritis Care & Research (free)


3 – 2018 Global Nutrition Report (free)

Commentaries: 2018 Global Nutrition Report reveals malnutrition is unacceptably high and affects every country in the world, but there is also an unprecedented opportunity to end it – UNICEF (free) AND ‘Diabolical’ diets: four in 10 children consume sugary drinks daily – The Guardian (free) AND ‘No country is untouched’: Global Nutrition Report highlights compounding malnutrition – Devex (free)


4 – Global Atlas of Cardiovascular Disease 2000-2016: The Path to Prevention and Control – Global Heart (free)


5 – Medical Screening Tests You Do and Don’t Need – Consumer Reports (free) (via @EricTopol)

“Some may be life-saving, but others can waste time and money—and pose risks”


6 – Current opinions for the management of asthma associated with ear, nose and throat comorbidities – European Respiratory Review (free)


7 – Viewpoint: The Challenges of Improving Treatments for Depression – JAMA (free)


8 – Outdoor Artificial Nighttime Light and Use of Hypnotic Medications in Older Adults: A Population-Based Cohort Study – Journal of Clinical Sleep Medicine (free)

Commentary: Light pollution may cause insomnia in older adults – American Academy of Sleep Medicine (free)


9 – Unscrambling the relations of egg and meat consumption with type 2 diabetes risk – American Journal of Clinical Nutrition (free)

Commentary: LLU School of Public Health study finds meat, not eggs, is linked to type 2 diabetes – Loma Linda University School of Public Health (free)

Related Studies: Red meat consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis – American Journal of Clinical Nutrition (free) AND Changes in Red Meat Consumption and Subsequent Risk of Type 2 Diabetes Mellitus: Three Cohorts of US Men and Women – JAMA Internal Medicine (free)


10 – Associations of Smoke‐Free Policies in Restaurants, Bars, and Workplaces With Blood Pressure Changes in the CARDIA Study – Journal of the American Heart Association (free)

News Release: Smoke-free policies associated with lower blood pressure – American Heart Association (free)

Editorial: Necessity of Preventing Cardiovascular Disease by Smoke‐Free Policies (free)

Commentaries: Smoking bans tied to lower blood pressure in non-smokers – Reuters (free) AND Smoking bans in restaurants, workplaces linked to lower SBP – Cardiovascular Business (free)

Related Study: Updating the evidence relating smoking bans to incidence of heart disease – Regulatory Toxicology and Pharmacology (free)


Fri, November 30 – 10 Stories of The Day!

30 Nov,2018


1 – The 2018 report of the Lancet Countdown on health and climate change: shaping the health of nations for centuries to come – The Lancet (free registration required)

Editorial: Humanising health and climate change (free)

Commentaries: Global warming will increase heat-related death and disease – study – Reuters (free) AND Climate change and air pollution damaging health and causing millions of premature deaths – International Institute for Applied Systems Analysis (free) AND 5 ways climate change is bad for your health – Imperial College London (free)

Related: Projections of Temperature-Related Excess Mortality Under Climate Change Scenarios (free study and commentaries) AND Quantifying Excess Deaths Related to Heatwaves Under Climate Change Scenarios (free study and commentaries)


2 – Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study – Journal of the American Heart Association (free)

Editorial: Spark That Lights the Fire: Infection Triggers Cardiovascular Event (free)

Commentary: Infections may be a ‘trigger’ for heart attack, stroke – American Heart Association News (free)


3 – Fluoroquinolones and the risk of aortopathy: A systematic review and meta-analysis – International Journal of Cardiology (free)

“…current fluoroquinolone use was significantly associated with increased risk of aortic aneurysm and dissection.”


4 – Progress Toward Regional Measles Elimination — Worldwide, 2000–2017 – Centers for Disease Control and Prevention (free)

Commentaries: Measles cases spike globally due to gaps in vaccination coverage – World Health Organization (free) AND Report: Measles spike triggered by vaccination gaps – CIDRAP (free) AND Measles cases surged globally in 2017 due to gaps in vaccine coverage, health agencies say – CNN (free)


5 – Cesarean delivery rate and staffing levels of the maternity unit – PLOS One (free)

Commentary: Staffing more doctors and midwives tied to lower C-section rates – Reuters (free)


6 – We’re Living Longer … But A Medical Journal Sees Many Causes For Alarm – NPR (free)

Related Editorial: GBD 2017: a fragile world – The Lancet (free)


7 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)

Commentaries: DRC’s 426-case Ebola outbreak now 2nd largest ever – CIDRAP (free) AND Ebola and War in the Democratic Republic of Congo: Avoiding Failure and Thinking Ahead – JAMA (free) AND Ramping Up the Response to Ebola – New England Journal of Medicine (free) AND Ebola outbreak in east Congo now world’s second biggest – Reuters (free)


8 – Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis – The BMJ (free)

Commentary: Many incidental findings spotted on MRIs, few turn out to be cancer – Reuters (free)

Related: Prevalence and outcomes of incidental imaging findings: umbrella review (free)


9 – Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Low-Dose Imipramine Alternative Treatment for Refractory Functional Dyspepsia – Clinical Advisor (free)


10 – Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Cardiovascular Toxicities Associated With Immune Checkpoint Inhibitor Treatment – The ASCO Post (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)


Thu, November 29 – 10 Stories of The Day!

29 Nov,2018


1 – ASH Clinical Practice Guidelines on Venous Thromboembolism – American Society of Hematology (free)

News Release: New clinical practice guidelines for venous thromboembolism (free)


2 – Principles for Patient and Family Partnership in Care: An American College of Physicians Position Paper – Annals of Internal Medicine (free)

News Release: American College of Physicians releases principles to guide patient partnership in health care (free)


3 – A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline (free)


4 – Attention Deficit–Hyperactivity Disorder and Month of School Enrollment – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: When starting school, younger children are more likely to be diagnosed with ADHD – Harvard Medical School (free) AND Youngest Children In A Class Are Most Likely To Get ADHD Diagnosis – NPR (free) AND Younger school entry could set stage for ADHD diagnosis – Associated Press (free)

Related: Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD (free study and commentaries)


5 – Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

Video Summary: Alirocumab and CV Events after Acute Coronary Syndrome (free)


6 – Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery – Cochrane Library (free)

Summary: Do blood thinner injections given after abdominal surgery further reduce blood clots if continued after discharge from the hospital? – Cochrane Library (free)


7 – Plan S: From Principles to Implementation. cOAlition S Releases Implementation Guidance on Plan S (free)

Commentary: Funders flesh out details of Europe’s bold open-access plan (free)

Related: In Win for Open Access, Two Major Funders Won’t Cover Publishing in Hybrid Journals (free commentaries) AND cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)


8 – Is our constant use of digital technologies affecting our brain health? We asked 11 experts – VOX (free)


9 – WHO Housing and health guidelines – World Health Organization (free)


10 – Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis – The Lancet Global Health (free)

Invited Commentary: Global childhood pneumonia: the good news, the bad news, and the way ahead (free)


Wed, November 28 – 10 Stories of The Day!

28 Nov,2018


1 – Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Invited Commentary: Statistics on the burden of dementia: need for stronger data – The Lancet (free)

“In 2016, globally, 43·8 million individuals lived with dementia, increased from 20.2 million in 1990; dementia was the fifth leading cause of death globally (2·4 million) and more women than men had dementia” (via @TheLancet see Tweet with infographic)


2 – Sex differences in faecal occult blood test screening for colorectal cancer – British Journal of Surgery (free)

Commentaries: Screen­ing for colorectal can­cer spares male pa­tients from in­tense treat­ments – University of Helsinki (free) AND FOBT Colorectal Cancer Screening Only Effective in Men – Medscape (free registration required)


3 – Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia: a retrospective cohort study – Canadian Medical Association Journal (free)

Commentaries: Study finds alternative to antipsychotic medication for seniors also has drawbacks – The Globe and Mail (free) AND Trazadone linked to more falls, major fractures in dementia patients – UPI (free) AND Trazadone associated with similar risk of falls and major fractures as antipsychotics in seniors with dementia – Canadian Medical Association Journal (free) AND Aggression in Dementia: Alternatives to Antipsychotics Also Have Side Effects – MedicalResearch.com (free)


4 – Review: Therapy and Management of Pneumocystis jirovecii – Infection – Journal of Fungi (free)

This article belongs to the Special Issue Treatments for Fungal Infections (free reviews)


5 – Arterial thrombosis in unusual sites: A practical review – European Journal of Haematology (free)


6 – Survey Snapshot: What Would Accelerate the Adoption of Value-Based Care? – NEJM Catalyst (free)


7 – Ten simple rules for collaboratively writing a multi-authored paper – PLOS Computational Biology (free) (via @Abraham_RMI)


8 – Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Some research may be encouraging ineffective prescriptions, says new study – McGill University (free)

“Our point is not to condemn these individual trials. Instead, we are saying that—when you zoom out and look at what’s happening at the level of the forest—the trees begin to look less healthy.” (from McGill University)


9 – Viewpoint: A Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia – JAMA Internal Medicine (free)


10 – Long-Term Protection After Fractional-Dose Yellow Fever Vaccination: Follow-up Study of a Randomized, Controlled, Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Study affirms fractional dosing with yellow fever vaccine – CIDRAP (free)

Related: Fractional-Dose Yellow Fever Vaccination (free research and perspective)


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