Open access


Fri, February 16 – 10 Stories of The Day!

16 Feb,2018


1 – WHO recommendations: intrapartum care for a positive childbirth experience – World Health Organization (free)

News release: Individualized, supportive care key to positive childbirth experience, says WHO (free)

Commentary: Give women more time to give birth, make choices – WHO – Reuters (free)


2 – Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) (free)

Commentary: Fecal transplants move into the mainstream to treat difficult infection – STAT (free)


3 – Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The PRESERVE trial – 2 Minute Medicine (free) AND Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine – NEJM Resident 360 (free)

“Among patients at high risk for renal complications who were undergoing angiography, there was no benefit of intravenous sodium bicarbonate over intravenous sodium chloride or of oral acetylcysteine over placebo for the prevention of death, need for dialysis, or persistent decline in kidney function at 90 days or for the prevention of contrast-associated acute kidney injury”.


4 – Review: Physical Activity in the Prevention and Treatment of Coronary Artery Disease – Journal of the American Heart Association (free for a limited period)


5 – Consumption of ultra-processed foods and cancer risk: results from NutriNet-Santé prospective cohort – The BMJ (free)

Editorial: Ultra-processed foods and cancer (free)

Commentaries: ‘Ultra-processed’ foods and cancer: Headlines show the right way, and the wrong way, to frame results from an observational study – HealthNewsReview (free) AND Expert reaction to study looking at highly processed foods and cancer – Science Media Centre (free)


6 – Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Edoxaban for Cancer-Associated Venous Thromboembolism (free)

Commentaries: Edoxaban Noninferior to Dalteparin for Cancer-Associated VTE – Physician’s First Watch (free) AND Oral Edoxaban Noninferior to Dalteparin for Cancer-Related Venous Thromboembolism – Cardiology Advisor (free)


7 – Mortality in single fathers compared with single mothers and partnered parents: a population-based cohort study – The Lancet Public Health (free)

Commentaries: Premature mortality in single fathers – The Lancet Public Health (free) AND Single fathers have highest risk of early death – OnMedica (free) AND Single Fathers Are More Likely to Die Early, Study Says – TIME (free)


8 – Risk of Dementia in Adults With Congenital Heart Disease: Population-Based Cohort Study – Circulation (free PDF)

Commentaries: Congenital heart defects linked to increased risk of dementia – American Heart Association News (free) AND Adult Survivors of Congenital Heart Disease at Increased Risk of Dementia – TCTMD (free)


9 – Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease – Circulation: Genomic and Precision Medicine (free)

Commentary: Genetic Risk Score May Best FH Variant for Predicting Early-Onset CAD – Medscape (free registration required)

“Another study suggests CAD will soon be predicted not by 1 gene (like FH) but groups of genes that can be combined into risk scores” (via @drjohnm see Tweet)


10 – Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes: A Systematic Review and Meta-analysis – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries: Could NOACs Have a Role for Secondary Prevention After STEMI? – TCTMD (free) AND Meta-Analysis: ACS Type Matters for DOAC Use in Secondary Prevention – MedPage Today (free registration required) AND Adding DOACs Beneficial for STEMI — Not Non-STEMI — But with Bleeding Risk – Physician’s First Watch (free)

63 STEMI patients would need to receive a DOAC to prevent one cardiovascular event, while 96 would need to be treated to cause one major bleeding event”. (from Physician’s First Watch)


Thu, February 15 – 10 Stories of The Day!

15 Feb,2018


1 – Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak — Preliminary Report – The New England Journal of Medicine (free)

A fractional dose containing one fifth of the standard dose was effective at inducing seroconversion, supporting the use of fractional-dose vaccination for outbreak control.


2 – Evidence-based clinical practice guidelines for inflammatory bowel disease – Journal of Gastroenterology (free)


3 – Medical News & Perspectives: Do All Patients Need β-Blockers After a Heart Attack? – JAMA (free for a limited period)


4 – The state of OA: a large-scale analysis of the prevalence and impact of Open Access articles – PeerJ (free)


5 – Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free)

Commentary: New Guidelines for Treating Checkpoint Inhibitor Toxicities – Medscape (free registration required)

Relate guideline: Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free) AND Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)


6 – Uterine Neoplasms, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology (free)


7 – New Dutch law to make all adults organ donors unless they opt out – CNN (free) AND Every Adult in This Country Is Now an Organ Donor Unless They Opt Out – TIME (free) AND Dutch law to make everyone organ donors unless they opt out – ABC News (free)


8 – Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Mild shock therapy may ease anxiety and depression, but not chronic pain – Reuters (free) AND Jury Still Out on CES for Depression, Anxiety, Pain, Insomnia – Medscape (free registration required)


9 – Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases: A Nested Case–Control Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Opioids may be associated with increased risk for serious invasive pneumococcal infections – ACP Internist (free) AND Opioids For Pain Can Exacerbate Pneumococcal Infections – MedicalResearch.com (free) AND Prescription Opioid Use Tied to Higher Pneumonia Risk – MedPage Today (free registration required)


10 – Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study – The Lancet Infectious Diseases (free)

Commentaries: Surgical site infection—the next frontier in global surgery – The Lancet Infectious Diseases (free) AND Poor nations have higher risk of surgical infections, including resistant ones – CIDRAP (free)


Wed, February 14 – 10 Stories of The Day!

14 Feb,2018


1 – Family Planning – A global handbook for providers: 2018 edition – World Health Organization (free)

News release: Updated and expanded guidance for family planning providers worldwide (free)


2 – Guideline: Antiarrhythmic drugs–clinical use and clinical decision making: a consensus document from EHRA, ESC, HRS, APHRS and ISCP (free)

Source: Antiarrhythmics: multinational consensus recommendations – Univadis (free registration required)


3 – Screening for Ovarian Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Screening for Ovarian Cancer in Asymptomatic Women (free) AND The Yet Unrealized Promise of Ovarian Cancer Screening (free) AND Is There a Future for Ovarian Cancer Screening? (free)

Author interview: USPSTF Recommendation: Screening for Ovarian Cancer (free audio)

“The USPSTF recommends against screening for ovarian cancer in asymptomatic women. (D recommendation) This recommendation applies to asymptomatic women who are not known to have a high-risk hereditary cancer syndrome”.


4 – Association of Combined Patterns of Tobacco and Cannabis Use in Adolescence With Psychotic Experiences – JAMA Psychiatry (free)

Commentaries: Risk of Psychotic Experiences Up With Teen Cannabis Use – Physician’s Briefing (free) AND Teen Pot Use Linked to Increased Risk for Psychotic Episodes – MedPage Today (free registration required)


5 – Randomized Trial of Dexamethasone Versus Prednisone for Children with Acute Asthma Exacerbations – The Journal of Pediatrics (link to abstract – $ for full-text)

Commentary: Asthma Exacerbation in Kids: A Trial of Two Steroids – Medscape (free registration required)

Related meta-analysis: Dexamethasone for Acute Asthma Exacerbations in Children: A Meta-analysis – Pediatrics (free PDF)

Related study in adults: A Randomized Controlled Noninferiority Trial of Single Dose of Oral Dexamethasone Versus 5 Days of Oral Prednisone in Acute Adult Asthma – Annals of Emergency Medicine (link to abstract – $ for full-text) AND Commentary: Single Dose Dexamethasone or 5 Days of Prednisone in Adult Asthmatics? – R.E.B.E.L.EM commentary (free full-text)


6 – Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer – New England Journal of Medicine (free)

Apalutamide improves castration resistant prostate CA survival compared with… placebo. Why wasn’t it compared w bicalutamide?” (via @RichardLehman1 see Tweet). See Richard Lehman’s point of view


7 – In Sweeping War on Obesity, Chile Slays Tony the Tiger – The New York Times (10 articles per month are free)


8 – One Health Approach is Critical to De-risk Human, Animal and Environmental Health – The World Bank (free)

See report: Operational Framework for Strengthening Human, Animal And Environmental Public Health Systems At Their Interface – The World Bank (free PDF)

Related review: The science behind One Health: at the interface of humans, animals, and the environment – Annals of the New York Academy of Sciences (free)


9 – Comprehensive geriatric assessment for older people admitted to a surgical service – Cochrane Library (free)

Summary: Does special assessment of older people getting surgery improve their recovery after surgery? – Cochrane Library (free)


10 – Cancer risk associated with chronic diseases and disease markers: prospective cohort study – The BMJ (free)

Commentaries: Study reveals substantial impact of chronic diseases on cancer risk – eCancer News (free) AND Chronic Disease Linked To Increased Risk of Cancer and Cancer Death – MedicalResearch.com (free) AND Double Trouble: These Diseases Could Raise Your Risk for Cancer – Live Science (free) AND Higher cancer risk from chronic diseases – OnMedica (free)


Tue, February 13 – 10 Stories of The Day!

13 Feb,2018


1 – Delayed umbilical cord clamping reduces hospital mortality for preterm infants – NIHR Signal (free)

Original article: Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (free)


2 – Effect of early and systematic integration of palliative care in patients with advanced cancer: a randomised controlled trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Early Integration of Palliative Care Improves Quality of Life in Advanced Cancer – Oncology Nurse Advisor (free)

Related Guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free) AND Commentary: Concurrent Palliative Care: Recommendations From the ASCO Clinical Practice Guideline – The ASCO Post (free)


3 – Infographic: ATLS Trauma Update 2018 (free) (via @CritCareReviews)


4 – The Hypertension Guideline War Is Not A Fake War – Cardiobrief (free)

Related: The Fake Hypertension War: Medical politics and mud fights – MedPage Today (free registration required)


5 – Overtesting and undertesting in primary care: a systematic review and meta-analysis – BMJ Open (free) (via @JackOSullivan3 and @KariTikkinen)


6 – Opinion: Heart Stents Are Useless for Most Stable Patients. They’re Still Widely Used – The New York Times (10 articles per month are free)


7 – State of The Art Review: The role of robotics in colorectal surgery – The BMJ (free for a limited period)


8 – Richard Lehman’s journal reviews, 12 February 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.


9 – Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study – The BMJ (free)

“Trimethoprim is associated with a greater risk of acute kidney injury and hyperkalaemia compared with other antibiotics used to treat UTIs, but not a greater risk of death”


10 – FIGO consensus guidelines on placenta accreta spectrum disorders – International Journal of Gynecology & Obstetrics

– Introduction (free)

– Epidemiology (free)

– Prenatal Diagnosis and Screening (free)

– Nonconservative surgical management (free)


Mon, February 12 – 10 Stories of The Day!

12 Feb,2018


1 – 10 threats to global health in 2018 – The World Health Organization (free)


2 – Environmental Noise and the Cardiovascular System – Journal of the American College of Cardiology (free for a limited period)

Commentaries: Everyday noises may cause increased risk of heart disease, experts say – ABC News (free) AND How Loud Noise Exposure Is Linked to Heart Disease – TIME (free) AND Traffic Noise Linked to Increased CVD Risk – Medscape (free registration required) AND Heart & hearing: Noise pollution tied to higher risk of stroke, MI – Cardiovascular Business (free)


3 – Energy Drinks: A Contemporary Issues Paper – American College of Sports Medicine (free)

Commentary: ACSM Announces New Recommendations and Warnings Regarding Safety of Energy Drinks – NewsWise (free)

Related: Energy and sports drinks in children and adolescents – Canadian Paediatric Society (free) AND Health Effects and Public Health Concerns of Energy Drink Consumption in the United States: A Mini-Review – Frontiers in Public Health (free)


4 – New Cochrane Systematic Reviews – Vaccines for Preventing Influenza and Its Complications

– In Healthy Children (free) / Summary (free)

– In The Elderly (free) / Summary (free)

– In Immunosuppressed Adults With Cancer (free) / Summary (free)

– In Healthy Adults (free) / Summary (free)


5 – Report: Weekly U.S. Influenza Surveillance – Centers for Disease Control and Prevention (free)

Commentaries: Flu-like illness in US reaches 2009 pandemic levels – CIDRAP (free) AND Flu Is Causing 1 in 10 American Deaths and Climbing – Bloomberg (free) AND This Flu Season Is the Worst in Nearly a Decade – The New York Times (10 articles per month are free)


6 – The Equity Impact Vaccines May Have On Averting Deaths And Medical Impoverishment In Developing Countries – Health Affairs (free)

Commentaries: Study: vaccines prevent not just disease, but also poverty – The Vaccine Alliance (free) AND For world’s poorest, vaccines prevent deaths, medical impoverishment – Harvard T.H. Chan School of Public Health (free)


7 – Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Commentary: New Guidelines Outline Management of Immunotherapy Side Effects – MedPage Today (free registration required) AND SITC Spearheads Initiative for Management of Immunotherapy-Related Side Effects – The ASCO Post (free)

Related review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)


8 – The open abdomen in trauma and non-trauma patients: WSES guidelines – World Journal of Emergency Surgery (free)


9 – Review compares effectiveness, cost, and safety of second-line drugs for diabetes – ACP Diabetes Monthly (free)

Original Report: New Drugs for Type 2 Diabetes: Second-Line Therapy – Canadian Agency for Drugs and Technologies in Health (free)


10 – Draft Recommendation Statement: Screening Syphilis Infection in Pregnant Women – U.S. Preventive Services Task Force (free)

Commentaries: USPSTF Recommends Screening Pregnant Women for Syphilis – American Academy of Family Physicians (free) AND USPSTF: Screening for Syphilis in Pregnant Women Beneficial – MPR (free) AND Syphilis Rising In Newborns, Pregnant Moms: USPSTF Reaffirms Mandatory Testing – American Council on Science and Health (free)


Fri, February 9 – 10 Stories of The Day!

9 Feb,2018


1 – 2018 annual review of the Blueprint list of priority diseases – World Health Organization (free) (via @equitylist)

Key actions: Diseases for which R&D preparedness activities are already in development – World Health Organization (free)


2 – Free online course. Starts 12 February 2018. The Lancet Maternal Health Series: Global Research and Evidence – London School of Hygiene & Tropical Medicine, via Future Learn

“Hear the latest expert evidence from The Lancet Maternal Health Series and learn what you can do to improve maternal healthcare”.


3 – Effectiveness of a childhood obesity prevention programme delivered through schools, targeting 6 and 7 year olds: cluster randomised controlled trial (WAVES study) – The BMJ (free)

Editorial: The failure of anti-obesity programmes in schools (free)

Commentary: Obesity crisis can’t be solved by schools – major new study – The Conversation (free) AND Schools are not the answer to childhood obesity epidemic, study shows – The Guardian (free)

“In the words of Winston Churchill, “However beautiful the strategy, you should occasionally look at the results.”” (from editorial)


4 – Review: The Management of Multi-vessel disease (MVD) in STEMI: The Science and Art of Decision-Making in STEMI – American College of Cardiology, Latest in Cardiology (free)


5 – Update: Stroke in Women: Recognizing Opportunities for Prevention and Treatment – Stroke (free PDF for a limited period)


6 – Update: Impact of Conventional Stroke Risk Factors on Stroke in Women – Stroke (free PDF for a limited period)


7 – Update: Stroke Risk Factors Unique to Women – Stroke (free PDF for a limited period)


8 – Five and 10 minute Apgar scores and risks of cerebral palsy and epilepsy: population based cohort study in Sweden – The BMJ (free)

Infographic: The vital ­first 10 minutes (free PDF)

Even slight changes within the normal Apgar score range (7-10) from five to 10 minutes have a major influence in the risks of cerebral palsy and epilepsy.


9 – Management of patients on antithrombotic agents undergoing emergency and elective endoscopy: joint Asian Pacific Association of Gastroenterology (APAGE) and Asian Pacific Society for Digestive Endoscopy (APSDE) practice guidelines – Gut (free)


10 – Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial – The Lancet child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Premature babies healthier when parents help with hospital care, study shows – The Guardian (free) AND Preemies Fared Better When Parents Helped with NICU Care – MedPage Today (free registration required) AND Parents’ care can help premature babies in hospital, says study – BBC News (free)


Thu, February 8 – 10 Stories of The Day!

8 Feb,2018


1 – Guideline: Pancreatic cancer in adults: diagnosis and management – National Institute for Health and Care Excellence (free)

News release: Pancreatic cancer patients should be offered early scans to avoid unnecessary surgery, says NICE (free)


2 – Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews – Cochrane Library (free)

Summary: Overview of Cochrane Reviews of interventions used during surgery for preventing surgical site infection (free)


3 – Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: For mortality prediction, qSOFA has poor sensitivity, moderate specificity, review finds – ACP Hospitalist (free) AND Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection – 2 Minute Medicine (free)


4 – Opinion: This flu season, physicians need to scrap the ‘martyr culture’ of working while sick – STAT (free) (via @CMichaelGibson)

Related study: Working with influenza-like illness: Presenteeism among US health care personnel during the 2014-2015 influenza season – American Journal of Infection Control (link to abstract – $ for full-text) AND Commentaries: Working while sick – ACP Internist (free) AND Health worker survey reveals many work during flu illness – CIDRAP (free)


5 – New cellphone and health studies don’t eliminate uncertainty – Science (free)

Other commentaries: Largest Animal Study of Cell Phone Radiation and Cancer Risk – Medscape (free registration required) AND High doses of cellphone radiation linked to some cancers in rats – STAT (free) AND Cell phone radiation: Could high exposure cause tumors? – Medical News Today (free)


6 – Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free)

Related Infographic: Date Night with the EHR – NEJM Catalyst (free)

Related Commentary: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free)

Related Guideline: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians(free)


7 – ISPOR 2018 – Top 10 Health Economics and Outcomes Research Trends (free PDF)

Commentary: Top 10 Trends Driving Healthcare in 2018 – NewsWise (free)


8 – Report: Global Monitoring of Disease Outbreak Preparedness: Preventing the Next Pandemics – Harvard Global Health Institute (free PDF)

See also: News Release (free) AND Summary report (free PDF)


9 – Preoperative exercise halves the postoperative complication rate in patients with lung cancer: a systematic review of the effect of exercise on complications, length of stay and quality of life in patients with cancer – British Journal of Sports Medicine (link to abstract – $ for full-text)

Commentaries: Regular exercise halves complication rate after lung cancer surgery – eCancer News (free) AND Lung Cancer Postoperative Complications Reduced With Preoperative Exercise – Pulmonology Advisor (free)


10 – Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke – JAMA (free for a period)

Commentaries: PFO Diagnosis Linked With Increased Risk of Perioperative Ischemic Stroke After Noncardiac Surgery – TCTMD (free) AND Preoperatively Diagnosed PFO and Perioperative Stroke – American College of Cardiology, Latest in Cardiology (free)


Wed, February 7 – 10 Stories of The Day!

7 Feb,2018


1 – Policy Statement: Recommended Childhood and Adolescent Immunization Schedules: United States, 2018 – American Academy of Pediatrics (free)

The Immunization Schedules for 2018 are available in the Red Book Online (free) and in the Centers for Disease Control and Prevention Website (free)


2 – Rapid Recommendations: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics)


3 – Report: E-cigarettes and heated tobacco products: evidence review – Public Health England (free PDF)

News release: PHE publishes independent expert e-cigarettes evidence review (free)

Commentaries: UK experts urge smokers to switch to e-cigs for big health gains – Reuters (free) AND E-cigarettes ‘should be on prescription’ – BBC News (free) AND Doctors should encourage smokers to switch to vaping – OnMedica (free)

See related report recently released by the National Academies of Sciences, Engineering, and Medicine (free report and commentaries)


4 – Effect of an In-Hospital Multifaceted Clinical Pharmacist Intervention on the Risk of Readmission: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Clinical Pharmacist Intervention Can Reduce ED Visits and Hospital Readmissions – MedicalResearch.com (free) AND Pharmacist-led extended medication review and follow-up on discharge may decrease risk of readmission – 2 Minute Medicine (free)


5 – EAU Guidelines on Assessment and Nonsurgical Management of Urinary Incontinence – European Urology (free)


6 – AASLD guidelines for the treatment of hepatocellular carcinoma – Hepatology (free)


7 – Richard Lehman’s journal review, 5 February 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.


8 – How Fake Surgery Exposes Useless Treatments – Scientific American (free)

Related: Sham surgeries: A tale of medical reversals & the role of the media – HealthNewsReview (free)


9 – To eat or to breathe? The answer is both! Nutritional management during noninvasive ventilation – Critical Care (free)


10 – Origins of the current outbreak of multidrug-resistant malaria in southeast Asia: a retrospective genetic study – The Lancet Infectious Diseases (free)

Commentaries: Drug-resistant malaria spreading fast in Southeast Asia – CIDRAP (free) AND Drug-resistant malaria will spread without urgent action, experts warn – The Guardian (free) AND Multidrug resistant malaria spread under the radar for years in Cambodia – Wellcome Sanger Institute (free)


Tue, February 6 – 10 Stories of The Day!

6 Feb,2018


1 – Recommended Immunization Schedule for Adults Aged 19 Years or Older, United States, 2018 – Annals of Internal Medicine (free)


2 – Viewpoint: Vitamin and Mineral Supplements: What Clinicians Need to Know – JAMA Internal Medicine (free for a period)


3 – Effect of Hot Tea Consumption and Its Interactions With Alcohol and Tobacco Use on the Risk for Esophageal Cancer: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Hot tea tied to higher cancer risk for smokers and drinkers – Reuters (free) AND Very hot tea can raise risk of oesophageal cancer, suggests study – The Guardian (free) AND Hot Tea and Increased Risk for Esophageal Cancer – Medscape (free registration required)


4 – Social exclusion heightens risk of death across many health conditions – NIHR Signal (free)

Original Article: Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis – The Lancet (free) AND Commentary: Inclusion health: addressing the causes of the causes (free) AND Review: What works in inclusion health: overview of effective interventions for marginalised and excluded populations (free registration required)


5 – Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis – Diabetic Medicine (link to abstract – $ for full-text)

Source: ACP Journal Wise ($)

“Metformin was associated with lower gestational weight gain and a lower risk of pre-eclampsia compared with insulin”


6 – Heparin-Induced Thrombocytopenia in the Patient Who Is Critically Ill – Chest (free)

Source: Critical Care Reviews Newsletter


7 – Richard Smith: Doctors and patients heading in opposite directions – The BMJ Opinion (free)

“Patients increasingly have multiple conditions, while doctors continue remorseless specialisation and subspecialisation. What are the consequences of this divergence?” (via @bmj_latest see Tweet)


8 – Hydroxyethyl-starch solutions (HES) should no longer be used in patients with sepsis or burn injuries or in critically ill patients – European Medicines Agency (free)

Press release: Hydroxyethyl-starch solutions for infusion to be suspended (free)

Source: EMA calls for hydroxyethyl starch solutions to be taken off market – The BMJ News ($)


9 – 5 ways poorly thought out health IT can worsen patient safety – KevinMD.com (free)


10 – Use of social media is associated with short sleep duration in a dose–response manner in students aged 11 to 20 years – Acta Paediatrica (link to abstract – $ for full-text)

Commentary: Social media use linked to lack of sleep in students – Wiley, via EurekAlert (free)

See also a recent Pediatrics supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn (series of free articles) and related articles on Social Media and Mental Health


Mon, February 5 – 10 Stories of The Day!

5 Feb,2018


1 – World Cancer Day (4 February 2018) – World Health Organization (free)

New Document: Guide to cancer early diagnosis – World Health Organization (free)

News Release: Guide to Cancer Early Diagnosis (free)

See other key cancer documents by WHO


2 – Intrauterine Growth Restriction. Guideline of the German Society of Gynecology and Obstetrics – Geburtshilfe und Frauenheilkunde (free)


3 – BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy – British Journal of Haematology (free)


4 – D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer in Stable Coronary Heart Disease Patients: The LIPID Study – Circulation (link to abstract – $ for full-text)

Commentary: D-dimer Predicts Long-Term Mortality, Vascular Events, Cancer – American College of Cardiology, Latest in Cardiology (free) AND D-Dimer Predicts CV, Cancer Mortality Over 16 Years in Patients With Stable CHD – Medscape (free registration required)


5 – Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free)

Related reviews: Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free)

Related guideline: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)


6 – Pediatrics Supplement – Congenital Zika Syndrome (via @greg_folkers)

– Public Health Approach to Addressing the Needs of Children Affected by Congenital Zika Syndrome (free)

– Zika and Public Health: Understanding the Epidemiology and Information Environment (free)

– Development of Infants With Congenital Zika Syndrome: What Do We Know and What Can We Expect? (free)

– Ophthalmologic Manifestations Associated With Zika Virus Infection (free)

– Motor Abnormalities and Epilepsy in Infants and Children With Evidence of Congenital Zika Virus Infection (free)

– The Likely Impact of Congenital Zika Syndrome on Families: Considerations for Family Supports and Services (free)


7 – One Day Your Mind May Fade. At Least You’ll Have a Plan – The New York Times (10 articles per month are free)

Free download: Health Directive for Dementia (free PDF) from Advanced Directive for Dementia

Source: New document allows advance planning for dementia – Univadis (free registration required)

“A Simple Way to Document the Medical Care You Would Want If You Had Dementia”


8 – A revolution in health care is coming – The Economist (a few articles per month are free) (via @equitylist)

“Welcome to Doctor You”


9 – A Multicomponent, Preschool to Third Grade Preventive Intervention and Educational Attainment at 35 Years of Age – JAMA Pediatrics (free)

Commentaries: Longer Early Childhood Intervention Linked To Greater Post-Secondary Attainment – MedicalResearch.com (free) AND Does Preschool Make a Long-Term Difference? – MedPage Today (free) AND Graduates of early childhood program show greater educational gains as adults – EurekAlert (free)


10 – Prevalence of Pulmonary Embolism in Patients With Syncope – JAMA Internal Medicine (free for a period)

Author Interview: Prevalence of Pulmonary Embolism in Patients With Syncope (free)

Commentaries: Prevalence of PE Low for Patients Presenting to ER With Syncope – Physician’s Weekly (free) AND Study Finds Pulmonary Embolus Rarely the Cause of Syncope – MedicalResearch.com (free)


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